Fungicidal efficacy of photodynamic therapy using methylene blue against Sporothrix globosa in vitro and in vivo

Li, Jinran

Fungicidal efficacy of photodynamic therapy using methylene blue against Sporothrix globosa in vitro and in vivo - 2019.


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Background Sporothrix schenckii strains are the aetiological agents of sporotrichosis, which is endemic in China. The most common clinical manifestation of sporotrichosis is cutaneous and subcutaneous nodular lesions with lymphangitis involvement. Currently, antifungal therapy is commonly used to treat sporotrichosis, however, drug resistance and complications are the major concerns, especially in patients who have asymptomatic liver injury or existing liver disorders, children, and pregnant women.

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