Influence of genetics and epigenetics on the process of muscle hypertrophy: a systematic review (notice n° 1010525)
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| fixed length control field | 03333cam a2200289 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250125140558.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Fajardo Colorado, Myriam Dianora |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Influence of genetics and epigenetics on the process of muscle hypertrophy: a systematic review |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2023.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 68 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | L’hypertrophie musculaire est l’augmentation de la taille du diamètre transversal des fibres musculaires. Bien que les mécanismes et les voies de signalisation qui régulent l’hypertrophie soient connus, on ne sait pas encore très bien dans quelle mesure la génétique et l’épigénétique contribuent à ce processus ; si les deux mécanismes participent conjointement ou si l’influence d’un événement est plus grande que celle de l’autre. Par conséquent, cette étude visait à examiner de manière approfondie la littérature et à tenter de déterminer le rôle des gènes et des mécanismes épigénétiques dans la régulation de l’hypertrophie musculaire associée à l’activité physique et/ou sportive. À cette fin, les bases de données Scopus et ScienceDirect ont été examinées, et les moteurs de recherche PubMed et Google Scholar ont été utilisés, où 25 articles répondaient aux critères d’inclusion. Les résultats ont démontré qu’il existe plusieurs gènes régulateurs de l’hypertrophie musculaire tels que MSTN, PGC-1 α, STARS, JunB, entre autres, ainsi que des polymorphismes génétiques, et une participation importante de la méthylation de l’ADN, qui ensemble contrôleraient les voies de signalisation et les réseaux de gènes importants pour le développement de ce processus. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Muscle hypertrophy is the increase in the size of the transverse diameter of muscle fibers. Although the mechanisms and signaling pathways that regulate hypertrophy are known, it is still unclear how much genetics and epigenetics contribute to this process; whether both mechanisms participate jointly, or whether there is a more significant influence of one event than the other. Therefore, this study aimed to extensively review the literature and determine the role of genes and epigenetic mechanisms in regulating muscle hypertrophy associated with physical activity and sport. For this purpose, the Scopus and ScienceDirect databases were reviewed, and the PubMed and Google Scholar search engines were used, where 25 articles met the inclusion criteria. Results demonstrated that there are several regulatory genes of muscle hypertrophy, such as MSTN, PGC-1 α, STARS, and JunB, among others, as well as genetic polymorphisms and vital participation of DNA methylation, which together would control signaling pathways and gene networks necessary for the development of this process. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | MSTN |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | méthylation |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | ADN |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | sport |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | MSTN |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | methylation |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | DNA |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | sport |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Correa Jaramillo, Rodney |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | González Arango, Luis Fernando |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Movement & Sport Sciences - Science & Motricité | 121 | 3 | 2023-09-05 | p. 59-72 | 2118-5735 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://shs.cairn.info/revue-movement-and-sport-sciences-2023-3-page-59?lang=en&redirect-ssocas=7080">https://shs.cairn.info/revue-movement-and-sport-sciences-2023-3-page-59?lang=en&redirect-ssocas=7080</a> |
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