Clitoral blood flow after use of gel containing L-arginine and L-citrulline (notice n° 1010971)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02377cam a2200277 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250125140717.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Lovie, K. |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Clitoral blood flow after use of gel containing L-arginine and L-citrulline |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2022.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 85 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | L-arginine and its precursor and metabolite, l-citrulline, are two amino acids involved in the production of nitric oxide (NO). As a result, they increase blood flow and have been used to treat male sexual dysfunction. We aimed to evaluate whether a topical gel containing l-arginine and l-citrulline could increase blood flow to the clitoris. Sonography of the clitoris was performed on a healthy 32-year-old volunteer before and after applying the gel externally to the vulva. The ‘‘before’’ scans were obtained using a neutral ultrasound gel (without larginine or l-citrulline). This allowed us to verify that the observations were due to the active ingredients of the gel, and not from massage associated with its application. Control images without gel could not be obtained, since acquisition of ultrasound images requires ultrasound gel in order to reduce acoustic impedance. The scans were obtained with a Philips LumifyTM ultrasound (Koninklijke Philips N.V., Amsterdam, Netherlands) with a L12-4 linear array transducer (4—12 MHz). Clitoral blood flow was assessed qualitatively (color Doppler images), as well as quantitatively (peak systolic velocity, end diastolic velocity, and resistive index of the deep artery of the clitoris). Clitoral blood flow and velocities increased after application of the gel containing l-arginine and l-citrulline at the time points assessed (5 and 15 minutes). Difficulty achieving clitoral stimulation is a major cause of sexual dysfunction. Clinicians can use these findings to counsel patients about using gels to increase clitoral blood flow. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Clitoris |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Arginine |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Sonography |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Citrulline |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Sonography |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Citrulline |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Clitoris |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Arginine |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marashi, A. |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marashi, A. |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Sexologies | 31 | 4 | 2022-04-01 | p. 410-412 | 1158-1360 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://shs.cairn.info/revue-sexologies-2022-4-page-410?lang=en&redirect-ssocas=7080">https://shs.cairn.info/revue-sexologies-2022-4-page-410?lang=en&redirect-ssocas=7080</a> |
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