Association between the Estrogen receptor β rs1256049 polymorphism and prostate cancer risk: A meta-analysis (notice n° 135202)
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| fixed length control field | 02278cam a2200193 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250112021250.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Gazzaz, Hassane |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Association between the Estrogen receptor β rs1256049 polymorphism and prostate cancer risk: A meta-analysis |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2023.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 6 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The estrogen receptor β (ESR-β) gene is suggested to have a growth-inhibiting role in prostate tissue and has been proposed as a new treatment to target prostate cancer (PCa). Previous studies have investigated the association between the ESR-β rs1256049 polymorphism and PCa, but findings have been inconsistent. Thus, this meta-analysis was performed to assess whether the ESR-β rs1256049 polymorphism is associated with an increased susceptibility to PCa. Eligible studies published before February 5, 2022 were systematically searched for in the PubMed, Web of Science, ScienceDirect and Google Scholar databases. The sample set was extracted from 11 case-control studies involving 9,390 cases and 10,057 controls on the link between ESR-β rs1256049 polymorphism and PCa susceptibility. In our overall meta-analysis, no significant link between rs1256049 and PCa risk was found under all genetic models. In subgroup analysis according to ethnicity, those of Asian origin had a significantly decreased cancer risk based on both the heterozygote genetic model (OR = 0.75, 95% CI = [0.63, 0.89] P = 0.01) and the dominant model (OR = 0.80, 95% CI [0.69, 0.94] P = 0.01). For the Caucasian group, there was a significantly increased risk observed in the allelic model (OR = 1.17, 95% CI = [1.04, 1.32] P = 0.01), heterozygote model (OR = 1.15, 95% CI = [1.01, 1.31] P = 0.03), and the dominant model (OR = 1.17, 95% CI = [1.03, 1.32] P = 0.01). Our results demonstrate that ESR-β r1256049 polymorphism may play a possible effect in PCa development in Caucasians and be a protective factor in Asians. |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | El Feniche, Mohammed |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ameur, Ahmed |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dami, Abdellah |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Annales de Biologie Clinique | 81 | 3 | 2023-05-01 | p. 280-288 | 0003-3898 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://shs.cairn.info/journal-annales-de-biologie-clinique-2023-3-page-280?lang=en">https://shs.cairn.info/journal-annales-de-biologie-clinique-2023-3-page-280?lang=en</a> |
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