The triad of diabetic ketoacidosis–acute pancreatitis–hypertriglyceridaemia: The value of genetic exploration (notice n° 135639)
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| fixed length control field | 01872cam a2200229 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250112021349.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Alarcan, Hugo |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | The triad of diabetic ketoacidosis–acute pancreatitis–hypertriglyceridaemia: The value of genetic exploration |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2022.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 90 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | A 16-year-old child with no medical history was admitted to the hospital emergency room for abdominal pain associated with polyuria-polydipsia and weight loss (baseline BMI: 25.4 kg/m2). A diagnosis of severe ketoacidosis was quickly suggested due to major metabolic acidosis, high ketonemia, and glycemia. Acute pancreatitis was then diagnosed due to a plasmatic lipase at more than ten times normal values, combined with severe hypertriglyceridemia above 100 mmol/L. The triad of diabetic ketoacidosis–acute pancreatitis–hypertriglyceridemia is rarely found in childhood and can have harmful consequences. The etiology of this disease is still not fully understood, as one can be both cause and consequence of the other. Genetic investigation of familial chylomicronemia served to invalidate the dyslipidemia etiology of this event. On the other hand, the association of a genetic variant of lipoprotein lipase leading to a decrease in its activity, with the insulinopenia of type 1 diabetes, most certainly triggered this episode of hypertriglyceridemia. |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Guillon, Antoine |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maillot, François |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Collin-Chavagnac, Delphine |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Christian, Andres |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Blasco, Hélène |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Piver, Eric |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Annales de Biologie Clinique | 80 | 3 | 2022-06-01 | p. 259-267 | 0003-3898 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://shs.cairn.info/journal-annales-de-biologie-clinique-2022-3-page-259?lang=en">https://shs.cairn.info/journal-annales-de-biologie-clinique-2022-3-page-259?lang=en</a> |
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