Ferritin as a predictive biomarker of severity in Covid-19 (notice n° 136071)
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| fixed length control field | 02064cam a2200205 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250112021451.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Perottet, Jérémy |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Ferritin as a predictive biomarker of severity in Covid-19 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2022.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 79 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: To prevent the crisis-level shortage of beds in hospitals and for more efficient support, it is necessary to early identify coronavirus disease-19 (Covid-19) patients at risk of developing a severe form of the disease. Objective: The aim of our study was to determine whether biological markers, including that of serum ferritin, could predict the severity of the Covid-19. Methods: One hundred and seventy-one patients with a positive diagnosis of Covid-19 by RT-PCR, who were admitted to Caen University Hospital, were included retrospectively. A serum ferritin measurement was performed for all patients. They were further classified either into a non-severe (n = 112) or a severe group (n = 59; those who were either hospitalized in the intensive care unit (ICU) and/or on mechanical ventilation, or who died). Results: Univariate analysis revealed a significant link between increased serum ferritin and CRP levels, obesity, CT scan lesions, pathological respiratory rate, decreased PaO2/FiO2 ratio, and the patient’s NEWS2 score. However, in a multivariate analysis, only CRP and obesity were associated with the severe form of Covid-19. Conclusion: While the pathological level of serum ferritin at admission is associated with the severe form of Covid-19, a combination of increased CRP levels and obesity would better predict the severity of the disease. |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gondolf, Clémentine |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Grandhomme, Frédérique |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Creveuil, Christian |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Allouche, Stéphane |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Annales de Biologie Clinique | 80 | 4 | 2022-07-01 | p. 363-368 | 0003-3898 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://shs.cairn.info/journal-annales-de-biologie-clinique-2022-4-page-363?lang=en">https://shs.cairn.info/journal-annales-de-biologie-clinique-2022-4-page-363?lang=en</a> |
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