Primary cutaneous aspergillosis with secondary invasive spread in an immunocompromised patient: A case report and literature review (notice n° 1528481)

détails MARC
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control field 20251012013131.0
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Personal name Adadi, Soukaina
Relator term author
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Title Primary cutaneous aspergillosis with secondary invasive spread in an immunocompromised patient: A case report and literature review
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Date of publication, distribution, etc. 2025.<br/>
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General note 49
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Summary, etc. Aspergillosis is a rare fungal infection, and primary cutaneous manifestations are particularly uncommon. The majority of cases occur in immunocompromised patients. Case presentation We report the case of a 14-year-old adolescent with diabetes who developed primary cutaneous aspergillosis after a stay in the intensive care unit due to decompensation of her condition. During her hospitalization, an ulceronecrotic papule appeared on the tip of her nose. Mycological analysis of the skin sample isolated and identified Aspergillus fumigatus. The clinical course was marked by hematogenous dissemination of the fungus, with cerebral involvement. The patient died of multiple organ failure. Conclusion The clinical lesions of primary cutaneous aspergillosis are nonspecific and generally present as various types of lesions, such as macules, papules, nodules, and pustules. This diversity and lack of specificity can lead to misdiagnosis and delayed treatment. Hematogenous dissemination, especially to distant sites such as the brain, is a particularly serious concern and should be promptly investigated in immunocompromised patients. Direct microscopy, microbiological culture, and histopathological examination are essential for establishing the diagnosis of primary cutaneous aspergillosis.
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Drani, Meryem
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Ben-saghroune, Hayat
Relator term author
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Personal name Tlamçani, Zineb
Relator term author
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Note Cahiers Santé Médecine Thérapeutique | 34 | 2 | 2025-05-13 | p. 128-134 | 2780-8858
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Uniform Resource Identifier <a href="https://shs.cairn.info/journal-cahiers-sante-medecine-therapeutique-2025-2-page-128?lang=en&redirect-ssocas=7080">https://shs.cairn.info/journal-cahiers-sante-medecine-therapeutique-2025-2-page-128?lang=en&redirect-ssocas=7080</a>

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