Biochemistry of Collagens, Laminins and Elastin (notice n° 1556574)

détails MARC
000 -LEADER
fixed length control field 02766cam a2200277zu 4500
003 - CONTROL NUMBER IDENTIFIER
control field FRCYB88973038
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20251020124201.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 251020s2019 fr | o|||||0|0|||eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9780128170687
035 ## - SYSTEM CONTROL NUMBER
System control number FRCYB88973038
040 ## - CATALOGING SOURCE
Original cataloging agency FR-PaCSA
Language of cataloging en
Transcribing agency
Description conventions rda
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Karsdal, Morten
245 01 - TITLE STATEMENT
Title Biochemistry of Collagens, Laminins and Elastin
Remainder of title Structure, Function and Biomarkers
Statement of responsibility, etc. ['Karsdal, Morten']
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Name of producer, publisher, distributor, manufacturer Academic Press
Date of production, publication, distribution, manufacture, or copyright notice 2019
300 ## - PHYSICAL DESCRIPTION
Extent p.
336 ## - CONTENT TYPE
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type code c
Source rdamdedia
338 ## - CARRIER TYPE
Carrier type code c
Source rdacarrier
520 ## - SUMMARY, ETC.
Summary, etc. There are 28 different collagens, with 46 unique chains, which allows for a collagen for each time and place. Some collagens are specialized for basement membrane, whereas others are the central structural component of the interstitial matrix. There are eight collagens among the 20 most abundant proteins in the body, which makes these molecules essential building blocks of tissues. In addition, lessons learned from monogenomic mutations in these proteins result in grave pathologies, exemplifying their importance in development. These molecules, and their post-translationally modified products serve as biomarkers of diseases in a range of pathologies associated with the extracellular matrix. Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers, Second Edition provides researchers and students current data on key structural proteins (collagens, laminins, and elastin), reviews on how these molecules affect pathologies, and information on how selected modifications of proteins can result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the extracellular matrix harbor cryptic signaling functions that may be viewed as endocrine function, and it highlights how this knowledge can be exploited to modulate fibrotic disease. - Provides an updated comprehensive introduction to collagen and structural proteins - Gives insight into emerging analytical technologies that can detect biomarkers of extracellular matrix degradation - Includes seven new chapters, including one on how collagen biomarkers are used in clinical research to support drug development and in precision medicine - Contains insights into the biochemical interactions and changes to structural composition of proteins in disease states - Proves the importance of proteins for collagen assembly, function, and durability
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Karsdal, Morten
856 40 - ELECTRONIC LOCATION AND ACCESS
Access method Cyberlibris
Uniform Resource Identifier <a href="https://international.scholarvox.com/netsen/book/88973038">https://international.scholarvox.com/netsen/book/88973038</a>
Electronic format type text/html
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