Treatment of psychological and behavioral symptoms in dementia with Lewy bodies and Parkinson’s disease dementia: Literature review and Delphi consensus (notice n° 1573057)

détails MARC
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control field 20251214025814.0
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Language code of text/sound track or separate title fre
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Personal name Blanc, Frédéric
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245 00 - TITLE STATEMENT
Title Treatment of psychological and behavioral symptoms in dementia with Lewy bodies and Parkinson’s disease dementia: Literature review and Delphi consensus
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Date of publication, distribution, etc. 2025.<br/>
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General note 90
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Summary, etc. Introduction Dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD) are frequently associated with psychological and behavioral symptoms (PBSs). Treatment for these symptoms is validated by varying levels of evidence Method We conducted a review of the literature on the treatment of PBSs in DLB and PDD from 2009 to 2023 and formulated treatment recommendations. When evidence from the literature was insufficient, the Delphi method was used to reach a consensus. Results The following recommendations were proposed: for intrusive hallucinations with insight preserved, donepezil or rivastigmine; for delusion and Capgras syndrome (Delphi), low doses of clozapine; for depression, sertraline, venlafaxine, or mirtazapine (Delphi); for REM sleep behavior disorder (RBD), immediate-release melatonin; for frontal syndrome, sertraline or paroxetine first, followed by trazodone (Delphi); for catatonia, lorazepam. Conclusion These recommendations should help improve the management of PBSs in DLB and PDD, thereby enhancing the quality of life of patients and caregivers.
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Brangier, Antoine
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Mouton, Aurélie
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Magnan, Nathaniel
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Rabiant, Kevin
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Auxire, Pauline
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Schorr, Benoit
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Roche, Jean
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Soto, Maria
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Delrieu, Julien
Relator term author
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Note Gériatrie et Psychologie Neuropsychiatrie du Vieillissement | 23 | 2 | 2025-09-20 | p. 235-253 | 2115-8789
856 41 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://stm.cairn.info/journal-geriatrie-et-psychologie-neuropsychiatrie-du-vieillissement-2025-2-page-235?lang=en&redirect-ssocas=7080">https://stm.cairn.info/journal-geriatrie-et-psychologie-neuropsychiatrie-du-vieillissement-2025-2-page-235?lang=en&redirect-ssocas=7080</a>

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