In vivo antipyretic activity, phytochemical and mineralogical composition of aqueous extracts of Baphia nitida (Fabaceae) and Trema orientalis (Cannabaceae) (notice n° 1573440)

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000 -LEADER
fixed length control field 02210cam a2200229 4500500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20251214030111.0
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title fre
042 ## - AUTHENTICATION CODE
Authentication code dc
100 10 - MAIN ENTRY--PERSONAL NAME
Personal name Bene, K.
Relator term author
245 00 - TITLE STATEMENT
Title In vivo antipyretic activity, phytochemical and mineralogical composition of aqueous extracts of Baphia nitida (Fabaceae) and Trema orientalis (Cannabaceae)
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Date of publication, distribution, etc. 2025.<br/>
500 ## - GENERAL NOTE
General note 80
520 ## - SUMMARY, ETC.
Summary, etc. Baphia nitida, minerals, pyrexia, phytocompounds, Trema orientalis Baphia nitida Lodd (Fabaceae) and Trema orientalis (Cannabaceae) are two medicinal plants used to reduce fever, harvested in March 2023 in the Agboville Department (Côte d’Ivoire). The aim of this study was to investigate the antipyretic effect, as well as the phytochemical and mineralogical composition of the leaves of these two species, to validate their use in traditional medicine. To do this, brewer’s yeast was used to induce hyperthermia in Wistar rats. They were then orally administered different doses of aqueous leaf extracts from the two plants. Phytochemical characterization using tube colorimetric tests revealed metabolites such as flavonoids, tannins, coumarins, saponins, polyphenols, sterols, and polyterpenes—phytocompounds known for their antipyretic activity. Fourteen minerals were measured using X-ray fluorescence spectrometry (XRF), with calcium, potassium, chlorine, and silicon found to be the most abundant. Regarding antipyretic activity, the aqueous extracts of Baphia nitida Lodd and Trema orientalis (Linn.) Blume significantly reduced pyrexia in rats induced by brewer’s yeast, with the Baphia nitida Lodd extract at 400 mg/kg of body weight showing greater activity than paracetamol. The Baphia nitida Lodd extract could be a promising candidate for the development of an antipyretic phytomedicine.
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Ouattara, A.
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Kone, N.
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Kande, B.
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Kadjo, A.F.
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Camara, Daouda
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Zirihi, G.N.
Relator term author
786 0# - DATA SOURCE ENTRY
Note Phytothérapie | 23 | 4 | 2025-10-21 | p. 177-186 | 1624-8597
856 41 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://stm.cairn.info/journal-phytotherapie-2025-4-page-177?lang=en&redirect-ssocas=7080">https://stm.cairn.info/journal-phytotherapie-2025-4-page-177?lang=en&redirect-ssocas=7080</a>

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