The aryl hydrocarbon receptor pathway plays a central role in the cutaneous response to pollutants (notice n° 159944)

détails MARC
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fixed length control field 02215cam a2200337 4500500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250112032505.0
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title fre
042 ## - AUTHENTICATION CODE
Authentication code dc
100 10 - MAIN ENTRY--PERSONAL NAME
Personal name Guillon, Cécile
Relator term author
245 00 - TITLE STATEMENT
Title The aryl hydrocarbon receptor pathway plays a central role in the cutaneous response to pollutants
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Date of publication, distribution, etc. 2023.<br/>
500 ## - GENERAL NOTE
General note 1
520 ## - SUMMARY, ETC.
Summary, etc. Short- and long-term exposure to atmospheric pollution has significant health effects. The skin is the organ directly in contact with pollutants and is responsible for protection of the organism. Particulate matter (PM) such as polycyclic aromatic hydrocarbons (PAHs) are the basis of certain pulmonary as well as dermatological complications. Pollution exacerbates certain illnesses such as atopic dermatitis and cancer, and it may also participate in delaying wound healing and in the occurrence of chronic ailments such as diabetes. The aryl hydrocarbon receptor (AhR) transcription factor, at the core of these responses to pollutants, is expressed by all cells of the skin. The AhR is subject to tight regulation that depends on its ligand. Pollutants act in a deleterious manner via the AhR, influencing the behaviour of keratinocytes as well as fibroblasts. Natural ligands, on the other hand, allow the noxious effects of pollution to be countered. This non-systematic review of the literature shows that modulation of AhR appears to be an excellent therapeutic approach to improve or stop the cutaneous problems linked to pollution.
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element skin
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element aryl hydrocarbon receptor
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element wound healing
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element pollution
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element atopic dermatitis
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element skin
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element aryl hydrocarbon receptor
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element wound healing
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element pollution
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element atopic dermatitis
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Meziani Mekki, Meriam
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Abdelli, Soraya
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Sigaudo Roussel, Dominique
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Bonod, Christelle
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Nosbaum, Audrey
Relator term author
786 0# - DATA SOURCE ENTRY
Note European Journal of Dermatology | 21 | 3 | 2023-09-26 | p. 305-311 | 1167-1122
856 41 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://shs.cairn.info/journal-european-journal-of-dermatology-2022-3-page-305?lang=en">https://shs.cairn.info/journal-european-journal-of-dermatology-2022-3-page-305?lang=en</a>

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