À propos d’un cas d’hydrocéphalie à pression normale idiopathique de découverte fortuite : caractérisation et possible devenir neuropsychologique (notice n° 1640414)
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| fixed length control field | 04639cam a2200265 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260201084331.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Lopis, Desirée |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | À propos d’un cas d’hydrocéphalie à pression normale idiopathique de découverte fortuite : caractérisation et possible devenir neuropsychologique |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2026.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 98 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | L’hydrocéphalie à pression normale idiopathique (HPNi) constitue un syndrome rare et hétérogène dont le profil neuropsychologique demeure mal caractérisé. Nous présentons ici le cas de M. L., 50 ans, chez qui une hydrocéphalie quadri-ventriculaire majeure (indice d’Evans = 0,45) a été découverte fortuitement à la suite d’un épisode transitoire de jargonophasie. Malgré l’absence de symptômes moteurs ou de troubles mnésiques, l’évaluation neuropsychologique révèle un syndrome dysexécutif cognitif léger, isolé, touchant la mémoire de travail auditivo-verbale et la flexibilité mentale réactive. Ce profil, compatible avec une atteinte fronto-sous-corticale discrète, soulève la question du lien entre dilatation ventriculaire et fonctionnement exécutif, dans un contexte d’étiologie multifactorielle (consommation chronique d’alcool, syndrome d’apnée du sommeil). Cette étude illustre la complexité diagnostique des formes « compensées » d’hydrocéphalie et l’intérêt d’une approche neuropsychologique fine pour distinguer un trouble dysexécutif primaire d’une comorbidité ou d’un vieillissement cognitif accéléré. D’un point de vue théorique, le cas de M. L. invite à considérer la plasticité cérébrale et les modèles connexionnistes comme cadre explicatif de la préservation cognitive observée malgré une réduction volumétrique cérébrale importante. Enfin, il souligne la nécessité d’un suivi neuropsychologique longitudinal systématique dans les HPNi asymptomatiques ou paucisymptomatiques. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | NIdiopathic normal pressure hydrocephalus (iNPH) is a heterogeneous and under-characterized syndrome, especially from a neuropsychological perspective. We present the case of M.L., a 50-year-old man who was found to have marked quadriventricular enlargement (Evans index = 0.45), incidentally identified following a transient episode of jargon aphasia. Despite the absence of gait disturbance, urinary symptoms, or functional impairment, neuropsychological evaluation revealed a mild, isolated dysexecutive syndrome affecting auditory–verbal working memory and reactive mental flexibility. Global cognition, episodic memory, processing speed, and visuoconstructive abilities were preserved. This pattern is consistent with a subtle fronto-subcortical dysfunction and raises questions about the causal relationship between ventricular dilation and executive deficits, particularly in light of potential confounding factors, including chronic alcohol use and untreated mild sleep apnea. From a clinical perspective, this case exemplifies the diagnostic challenges posed by “compensated” iNPH, in which severe ventriculomegaly may be present despite minimal or absent clinical manifestations. From a theoretical perspective, the preservation of cognitive efficiency despite significant cerebral volume reduction supports a connectionist view of brain organization and highlights the role of neuroplastic mechanisms in functional compensation. This report underscores the importance of systematic and detailed neuropsychological assessment in suspected or incidental iNPH, as brief cognitive screenings (e.g., MMSE) may fail to detect subtle executive dysfunctions. Longitudinal cognitive monitoring is warranted to clarify the clinical trajectory and potential transition toward neurodegenerative processes. By documenting this rare asymptomatic iNPH case, the study contributes to refining the neuropsychological phenotype of the disorder and highlights the critical need to integrate cognitive evaluation into diagnostic and follow-up protocols for iNPH. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | découverte fortuite |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | hydrocéphalie idiopathique à pression normale |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | troubles neurocognitifs |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | idiopathic normal pressure hydrocephalus |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | incidental discovery |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | neurocognitive disorders |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Blin, Jérôme |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Moroni, Christine |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Revue de neuropsychologie | Volume 17 | 4 | 2026-01-30 | p. 247-255 | 2101-6739 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://stm.cairn.info/revue-revue-de-neuropsychologie-2025-4-page-247?lang=fr&redirect-ssocas=7080">https://stm.cairn.info/revue-revue-de-neuropsychologie-2025-4-page-247?lang=fr&redirect-ssocas=7080</a> |
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