Présentation (notice n° 1644021)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03189cam a2200181 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260208000933.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Rappeneau, Virginie |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Présentation |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2025.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 17 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Reçu le 11 septembre 2025 Le comportement social est fondamental pour la survie et l’adaptation, et repose sur des mécanismes neurobiologiques complexes au sein desquels l’ocytocine (OT) et la dopamine (DA) jouent un rôle central dans la régulation de l’attachement social, de la motivation et de la récompense. Cette revue intègre les avancées récentes sur les interactions OT – DA dans des contextes sociaux reproductifs et non reproductifs, en soulignant leur influence bidirectionnelle au niveau des principaux circuits de la récompense, incluant le noyau accumbens, l’aire tegmentale ventrale, l’amygdale et le cortex préfrontal médian. Nous examinons également comment les psychostimulants, tels que la cocaïne et les amphétamines, perturbent cet équilibre, en modifiant la priorisation entre les récompenses associées à ces drogues et celles issues des interactions sociales, ce qui conduit à une altération des liens sociaux. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Social behaviour is fundamental to survival and adaptation, relying on complex, interacting neurobiological systems in which the neuropeptide oxytocin (OT) and the neurotransmitter dopamine (DA) play pivotal roles in regulating social bonding, motivation, and reward processing. This review synthesises recent advances in understanding the bidirectional interactions between OT and DA within key nodes of the brain’s reward circuitry, including the nucleus accumbens, ventral tegmental area, amygdala, and medial prefrontal cortex. We examine how these interactions support a wide range of social behaviours in humans and animals, from reproductive bonds such as pair bonding and parental care to non-reproductive interactions like social exploration, cooperation, and aggression. A central focus is the disruptive impact of psychostimulants (e.g., cocaine, amphetamines) on OT – DA balance in rodents. These substances alter DA signalling, shifting reward valuation and reducing the prioritisation of natural social rewards while increasing the drive for psychostimulant-seeking behaviour. This imbalance impairs social motivation and bonding. Importantly, positive social interactions can serve as competing natural rewards that prevent, and in some cases reverse, psychostimulant-seeking behaviours, highlighting the therapeutic potential of targeting OT – DA pathways. By integrating findings from animal models and human studies, this review proposes a framework for understanding how the brain arbitrates between social and pharmacological rewards, and how this balance is modulated by internal states, environmental factors, and the pathological effects of addictive substances. |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Castillo Díaz, Fernando |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Revue d'Histoire de l'Énergie | 14 | 1 | 2025-12-10 | p. 1-1 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://stm.cairn.info/revue-revue-dhistoire-de-lenergie-2025-1-page-1?lang=fr&redirect-ssocas=7080">https://stm.cairn.info/revue-revue-dhistoire-de-lenergie-2025-1-page-1?lang=fr&redirect-ssocas=7080</a> |
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