Thromboses veineuses et multi- ou poly-Omics : vers une compréhension intégrée et une médecine personnalisée (notice n° 1725209)
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| fixed length control field | 03327cam a2200481 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260322002634.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Andrès, Emmanuel |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Thromboses veineuses et multi- ou poly-Omics : vers une compréhension intégrée et une médecine personnalisée |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2026.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 46 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Les thromboses veineuses (TV), comprenant la thrombose veineuse profonde (TVP) et l’embolie pulmonaire (EP), représentent un problème de santé publique majeur en raison de leur morbimortalité élevée. La complexité physiopathologique des TV, impliquant une interaction entre facteurs génétiques, environnementaux, inflammatoires et métaboliques, nécessite des approches holistiques pour une meilleure compréhension. Les technologies multi- ou poly-omics, qui intègrent données génomiques, transcriptomiques, protéomiques, métabolomiques et épigénétiques, permettent de décrypter les mécanismes moléculaires sous-jacents à la formation des thromboses. Cet article passe en revue les apports majeurs de ces approches dans l’étude des TV, les biomarqueurs identifiés, les voies pathogéniques impliquées, ainsi que les perspectives offertes pour la médecine personnalisée. Les défis méthodologiques et les axes de recherche futurs sont également discutés. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Venous thrombosis (VT), including deep vein thrombosis (DVT) and pulmonary embolism (PE), represents a major public health problem due to its high morbidity and mortality rates. The pathophysiological complexity of VTs, involving an interaction between genetic, environmental, inflammatory and metabolic factors, requires holistic approaches for a better understanding. Multi- or poly-omics technologies, which integrate genomic, transcriptomic, proteomic, metabolomic and epigenetic data, make it possible to decipher the molecular mechanisms underlying the formation of thrombosis. This article reviews the major contributions of these approaches to the study of VTs, the biomarkers identified, the pathogenic pathways involved, and the prospects for personalised medicine. Methodological challenges and future research directions are also discussed. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | biomarqueurs |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | embolie pulmonaire |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | épigénomique |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | génomique |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | médecine personnalisée |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | métabolomique |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | multi-omics |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | protéomique |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | thrombose veineuse |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | thrombose veineuse profonde |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | transcriptomique |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | biomarkers |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | deep vein thrombosis |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | epigenomics |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | genomics |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | metabolomics |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | multi-omics |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | personalised medicine |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | proteomics |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | pulmonary embolism |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | transcriptomics |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | venous thrombosis |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Terrade, Jean Edouard |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jannot, Xavier |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lavigne, Thierry |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lorenzo-Villalba, Noël |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Cahiers Santé Médecine Thérapeutique | 35 | 1 | 2026-03-16 | p. 46-51 | 2780-8858 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://stm.cairn.info/revue-cahiers-sante-medecine-therapeutique-2026-1-page-46?lang=fr&redirect-ssocas=7080">https://stm.cairn.info/revue-cahiers-sante-medecine-therapeutique-2026-1-page-46?lang=fr&redirect-ssocas=7080</a> |
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