Associations de thérapies ciblées : le futur des MICI ? (notice n° 1824427)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02375cam a2200313 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260329003421.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Amiot, Aurélien |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Associations de thérapies ciblées : le futur des MICI ? |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2024.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 8 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | A growing number of patients with inflammatory bowel diseases (IBD) experienced failure of targeted therapies (monoclonal antibodies and small molecules). Combined targeted therapy is increasingly used for patients with refractory IBD allowing multimodal control of inflammation and restoration of epithelial homeostasis. This review compiles evidences for using combined targeted therapies including data from retrospective cohort studies and early-phase randomized controlled trials. This review also discusses limitations of current knowledge on ideal candidate and optimal use of combined targeted therapy. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Malgré d’immenses progrès, il persiste une proportion non négligeable de patients atteints de maladies inflammatoires chroniques de l’intestin pour lesquels les thérapies ciblées (anticorps monoclonaux et petites molécules) ne permettent pas d’aboutir à un contrôle satisfaisant de leur maladie. L’association de thérapies ciblées est une option de plus en plus utilisée afin de contrôler de façon simultanée plusieurs voies d’inflammation. Dans cette revue, nous abordons les données disponibles concernant les associations de thérapies ciblées au cours des maladies inflammatoires chroniques de l’intestin ainsi que les zones d’ombre qui nous restent à résoudre : Quelle association ? Pour quel patient ? Selon quelle séquence ? |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | biothérapie |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | maladie de Crohn |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | maladie inflammatoire chronique de l’intestin |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | petite molécule |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | rectocolite hémorragique |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | thérapie ciblée |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | biologic |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | combined targeted therapy |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Crohn’s disease |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | inflammatory bowel disease |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | small molecules |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | ulcerative colitis |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Hépato-Gastro & Oncologie Digestive | 31 | 8 | 2024-10-02 | p. 822-826 | 2115-3310 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://stm.cairn.info/revue-hepato-gastro-et-oncologie-digestive-2024-8-page-822?lang=fr&redirect-ssocas=7080">https://stm.cairn.info/revue-hepato-gastro-et-oncologie-digestive-2024-8-page-822?lang=fr&redirect-ssocas=7080</a> |
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