Efficacy of oxomemazine in treating cough: Systematic review and meta-analysis of randomized controlled trials (notice n° 1848635)

détails MARC
000 -LEADER
fixed length control field 01831cam a2200205 4500500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20260329010013.0
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title fre
042 ## - AUTHENTICATION CODE
Authentication code dc
100 10 - MAIN ENTRY--PERSONAL NAME
Personal name Bacon, Trystan
Relator term author
245 00 - TITLE STATEMENT
Title Efficacy of oxomemazine in treating cough: Systematic review and meta-analysis of randomized controlled trials
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Date of publication, distribution, etc. 2025.<br/>
500 ## - GENERAL NOTE
General note 18
520 ## - SUMMARY, ETC.
Summary, etc. Background: Cough is the most common presenting symptom for consulting in primary care. Oxomemazine is the second most reimbursed medication in France, among those approved for the symptomatic treatment of coughs. Objective: The aim of this study was to assess the efficacy of oxomemazine in treating cough. Methods: Systematic review and meta-analysis of randomized controlled trials (RCTs), according to the Rebuild the Evidence Base (REB) protocol. We included clinical trials comparing oxomemazine with a placebo or active controls in treating cough. We searched the following databases and registries to identify studies: Medline, Cochrane Central Register of Controlled Trials (CENTRAL), Embase, International Clinical Trials Registry Platform (ICTRP), and ClinicalTrials.gov. Results: None of the RCTs had a low risk of bias. In accordance with the REB protocol, no meta-analysis was carried out. Conclusion: This systematic review of the literature concludes that oxomemazine has not been adequately assessed in the treatment of cough and that there is no evidence of clinical efficacy according to the REB method.
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Blanchard, Clara
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Dubois, Estelle
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Vaillant-Roussel, Hélène
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Boussageon, Rémy
Relator term author
786 0# - DATA SOURCE ENTRY
Note Médecine | 20 | 10 | 2025-01-14 | p. 469-475 | 1777-2044
856 41 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://stm.cairn.info/journal-medecine-2024-10-page-469?lang=en&redirect-ssocas=7080">https://stm.cairn.info/journal-medecine-2024-10-page-469?lang=en&redirect-ssocas=7080</a>

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