Antiproliferative activity of protopine extract from Fumaria agraria against human lung cancer cell lines (notice n° 197706)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01250cam a2200181 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250112050225.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Bougoffa-Sadaoui, K. |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Antiproliferative activity of protopine extract from Fumaria agraria against human lung cancer cell lines |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2023.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 52 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Few studies have reported on the antitumor effects of isoquinoline alkaloids, particularly protopine, a major component of Fumaria agraria. The aim of our study was to determine the cytotoxic effect of protopine, extracted through fractionation of the aerial part of Fumaria agraria, on two lung cancer cell lines, NCI-H23 and NCI-H460. The basic fraction containing protopine (60.7%) exhibited cytotoxicity against both lung cancer cell lines studied. The cell line NCI-H460 was more sensitive after 72 hours of treatment with protopine, with an IC50 of 08.5 ± 0.09 μM, compared to the cell line NCI-H23 (IC50 = 14.8 ± 0.03 μM). |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maiza-Benabdesselam, F. |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hadouchi, Olivier |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Phytothérapie | 21 | 2-3 | 2023-04-01 | p. 102-107 | 1624-8597 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://shs.cairn.info/journal-phytotherapie-2023-2-3-page-102?lang=en">https://shs.cairn.info/journal-phytotherapie-2023-2-3-page-102?lang=en</a> |
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