Non-fistulizing perianal lesions in Crohn’s disease: A practical review and therapeutic implications (notice n° 2053483)

détails MARC
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control field 20260405002029.0
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Personal name Prothe, Carole
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Title Non-fistulizing perianal lesions in Crohn’s disease: A practical review and therapeutic implications
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Date of publication, distribution, etc. 2026.<br/>
500 ## - GENERAL NOTE
General note 38
520 ## - SUMMARY, ETC.
Summary, etc. Despite their frequency, non-fistulizing perianal lesions in Crohn’s disease remain underexplored. In contrast to fistulas and abscesses, their management is based on poorly standardized data. Their polymorphic clinical presentation can delay diagnosis. Clinical examination is essential and should be complemented by pelvic MRI to exclude underlying complications such as fistulas or abscesses. Treatment primarily relies on anti-TNFα agents, often in combination with immunosuppressants. Other biologic therapies, including JAK inhibitors, offer promising prospects, despite a low level of evidence with limited clinical data on non-fistulizing lesions available. Surgery is reserved for fibrotic lesions or degenerative complications. Long-term follow-up is mandatory due to the risk of anal cancer in chronic cases. This mini review provides a practical overview of the diagnostic, evaluative, and therapeutic strategies for these underrecognized manifestations of perianal Crohn’s disease.
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Fathallah, Nadia
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Barré, Amélie
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Personal name Pommaret, Élise
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Rentien, Anne-Laure
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Roland, Déborah
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Alam, Amine
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Skoufou, Maria
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Benfredj, Paul
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name de Parades, Vincent
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Note Hépato-Gastro & Oncologie Digestive | 33 | 1 | 2026-02-10 | p. 20-30 | 2115-3310
856 41 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://stm.cairn.info/journal-hepato-gastro-oncologie-digestive-2026-1-page-20?lang=en&redirect-ssocas=7080">https://stm.cairn.info/journal-hepato-gastro-oncologie-digestive-2026-1-page-20?lang=en&redirect-ssocas=7080</a>

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