The cutaneous virome: From virology to personalized medicine (notice n° 234396)
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fixed length control field | 02024cam a2200229 4500500 |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20250112063602.0 |
041 ## - LANGUAGE CODE | |
Language code of text/sound track or separate title | fre |
042 ## - AUTHENTICATION CODE | |
Authentication code | dc |
100 10 - MAIN ENTRY--PERSONAL NAME | |
Personal name | Dominguez-Lafage, Clément |
Relator term | author |
245 00 - TITLE STATEMENT | |
Title | The cutaneous virome: From virology to personalized medicine |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Date of publication, distribution, etc. | 2023.<br/> |
500 ## - GENERAL NOTE | |
General note | 73 |
520 ## - SUMMARY, ETC. | |
Summary, etc. | The cutaneous virome, defined as the collection of viruses detected in the skin, constitutes a significant part of the microbiota. A more recent discovery than bacterial flora, the existence of the cutaneous virome was unveiled through recent metagenomic studies. The virome of normal human skin is dominated by bacteriophages, Papillomaviridae—whose genomic diversity has proven extraordinary—and Polyomaviridae. Many viral genomes within this virome remain unidentified. The composition of the cutaneous virome has been shown to be strictly individual and relatively stable over time, reflecting its close adaptation to an individual’s genetics, lifestyle, and finely evolved mechanisms of immunological tolerance. Still underexplored, the cutaneous virome and its interactions with other microbiota microorganisms and with the host are attracting growing interest. Indeed, constitutional or acquired alterations in the homeostasis between the commensal virome and the skin, ranging from sub-clinical viral dysbiosis to severe transformation of keratinocytes or adnexal cells, have been observed. These recent findings are driving the search for innovative solutions to measure or even modulate its pathological expression, with promising prospects for personalized medicine. |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Laganà, Marta |
Relator term | author |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Gesbert, Franck |
Relator term | author |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Marin-Esteban, Viviana |
Relator term | author |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Schlecht-Louf, Géraldine |
Relator term | author |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Bachelerie, Françoise |
Relator term | author |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Deback, Claire |
Relator term | author |
786 0# - DATA SOURCE ENTRY | |
Note | Virologie | 27 | 6 | 2023-11-01 | p. 333-354 | 1267-8694 |
856 41 - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | <a href="https://shs.cairn.info/journal-virologie-2023-6-page-333?lang=en">https://shs.cairn.info/journal-virologie-2023-6-page-333?lang=en</a> |
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