The cutaneous virome: From virology to personalized medicine (notice n° 234396)

détails MARC
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control field 20250112063602.0
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Language code of text/sound track or separate title fre
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100 10 - MAIN ENTRY--PERSONAL NAME
Personal name Dominguez-Lafage, Clément
Relator term author
245 00 - TITLE STATEMENT
Title The cutaneous virome: From virology to personalized medicine
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Date of publication, distribution, etc. 2023.<br/>
500 ## - GENERAL NOTE
General note 73
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Summary, etc. The cutaneous virome, defined as the collection of viruses detected in the skin, constitutes a significant part of the microbiota. A more recent discovery than bacterial flora, the existence of the cutaneous virome was unveiled through recent metagenomic studies. The virome of normal human skin is dominated by bacteriophages, Papillomaviridae—whose genomic diversity has proven extraordinary—and Polyomaviridae. Many viral genomes within this virome remain unidentified. The composition of the cutaneous virome has been shown to be strictly individual and relatively stable over time, reflecting its close adaptation to an individual’s genetics, lifestyle, and finely evolved mechanisms of immunological tolerance. Still underexplored, the cutaneous virome and its interactions with other microbiota microorganisms and with the host are attracting growing interest. Indeed, constitutional or acquired alterations in the homeostasis between the commensal virome and the skin, ranging from sub-clinical viral dysbiosis to severe transformation of keratinocytes or adnexal cells, have been observed. These recent findings are driving the search for innovative solutions to measure or even modulate its pathological expression, with promising prospects for personalized medicine.
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Laganà, Marta
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Gesbert, Franck
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Marin-Esteban, Viviana
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Schlecht-Louf, Géraldine
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Bachelerie, Françoise
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Deback, Claire
Relator term author
786 0# - DATA SOURCE ENTRY
Note Virologie | 27 | 6 | 2023-11-01 | p. 333-354 | 1267-8694
856 41 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://shs.cairn.info/journal-virologie-2023-6-page-333?lang=en">https://shs.cairn.info/journal-virologie-2023-6-page-333?lang=en</a>

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