Coxsackievirus B infection and pathogenesis of type 1 diabetes (notice n° 234785)
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| fixed length control field | 01841cam a2200277 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250112063653.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Nekoua, Magloire Pandoua |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Coxsackievirus B infection and pathogenesis of type 1 diabetes |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2022.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 23 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Epidemiological and experimental studies suggest that enteroviruses (EVs), particularly coxsackieviruses B (CVBs), are likely to trigger or accelerate the onset of islet autoimmunity and the development of type 1 diabetes (T1D) in genetically susceptible individuals. Several mutually non-exclusive mechanisms have been proposed to explain the involvement of CVBs in the pathogenesis of T1D. CVBs can infect and persist in the intestine, thymic cells, monocytes/macrophages, ductal cells, and pancreatic β-cells, leading to structural or functional alterations of these cells. A chronic inflammatory response and disruption of tolerance toward β-cells due to CVB infections encourage the recruitment and activation of pre-existing autoreactive T-cells and the destruction of β-cells. Vaccines and therapeutic strategies to control EV infections have been developed and open up possibilities for the prevention or treatment of T1D. |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mercier, Ambroise |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Vergez, Inès |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Morvan, Corentin |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mbani, Chaldam Jespere |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sane, Famara |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lobert, Delphine |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Engelmann, Ilka |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Romond, Marie-Bénédicte |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Alidjinou, Enagnon Kazali |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hober, Didier |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Virologie | 26 | 6 | 2022-11-01 | p. 415-430 | 1267-8694 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://shs.cairn.info/journal-virologie-2022-6-page-415?lang=en">https://shs.cairn.info/journal-virologie-2022-6-page-415?lang=en</a> |
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