Refractory peptic esophageal strictures: Observations at the gastroenterology department of Fes (notice n° 416408)

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control field 20250119115620.0
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Personal name Hamdoun, Fatima-Zahra
Relator term author
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Title Refractory peptic esophageal strictures: Observations at the gastroenterology department of Fes
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Date of publication, distribution, etc. 2022.<br/>
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General note 19
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Summary, etc. Peptic stenosis (PS) is a benign complication of gastroesophageal reflux disease (GERD). Several methods are used to treat it, including endoscopic dilation combined with antisecretory treatment. If there is no improvement after 3 to 5 dilations, alternative therapy should be considered. The aim of this study is to evaluate the predictive factors for the occurrence of refractory esophageal stenosis. Methods This was a retrospective study spread over a period of 16 years between January 2002 and March 2019, including all patients presenting with dysphagia ± regurgitation with endoscopic and/or radiological presentations indicative of peptic stenosis. Refractory strictures were defined by strictures requiring more than five sessions with short recurrence intervals (less than 4 weeks). Results Of the 123 patients who underwent endoscopic dilation for peptic stenosis, 13% (N = 16) presented with refractory stenosis. The mean age was 53.5 years [17-86]. The M/F sex ratio was 4 with male predominance. Tobacco use was found in 19% (N = 3) and alcohol in 1 patient. In all of our patients we noted chronic gastroesophageal reflux with a mean duration of 6.75 years [1– 17], regurgitation in 75% (N = 12), and heartburn in 19% (N = 3). Dysphagia was mixed in 25% (N = 4). Endoscopy revealed impassable stenosis in 81% (N = 13) and double stenosis in 6% (N = 1). Three quarters of our patients were dilated by progressive diameter candles. The mean number of dilations was 3.1 ± 1.92 sessions/person. After 5 endoscopic dilations, only 37% (N = 6) underwent surgery, and only one patient had an esophageal prosthesis; the other patients continued the endoscopic dilation sessions. Upon univariate and multivariate analysis, refractory stenosis was found to be significantly associated with the duration of gastroesophageal reflux (p = 0.01) and poor adherence to consolidation treatment based on proton pump inhibitors (P = 0.005). Conclusion Refractory strictures were present in 13% of the patients in our group, including patients with long-standing chronic gastroesophageal who had not received PPI-based consolidation therapy.
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Personal name Abid, Hakima
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name El Yousfi, Mounia
Relator term author
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Personal name El Abkari, Mohamed
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Ibrahimi, Adil
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Benajah, Dafr-Allah
Relator term author
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Personal name Lahmidani, Nada
Relator term author
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Note Cahiers Santé Médecine Thérapeutique | 31 | 1 | 2022-01-01 | p. 35-39 | 2780-8858
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Uniform Resource Identifier <a href="https://shs.cairn.info/journal-cahiers-sante-medecine-therapeutique-2022-1-page-35?lang=en&redirect-ssocas=7080">https://shs.cairn.info/journal-cahiers-sante-medecine-therapeutique-2022-1-page-35?lang=en&redirect-ssocas=7080</a>

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