HER2+ gastroesophageal adenocarcinomas: Current standards and therapeutic prospects (notice n° 498630)

détails MARC
000 -LEADER
fixed length control field 01295cam a2200181 4500500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250121081700.0
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title fre
042 ## - AUTHENTICATION CODE
Authentication code dc
100 10 - MAIN ENTRY--PERSONAL NAME
Personal name Quesada, Stanislas
Relator term author
245 00 - TITLE STATEMENT
Title HER2+ gastroesophageal adenocarcinomas: Current standards and therapeutic prospects
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Date of publication, distribution, etc. 2022.<br/>
500 ## - GENERAL NOTE
General note 10
520 ## - SUMMARY, ETC.
Summary, etc. Esogastric adenocarcinomas (EGAs) are characterized in 10–20% of cases by overexpression and/or amplification of HER2. Current standard treatment for HER2+ EGAs relies on trastuzumab (an anti-HER2 antibody) plus a doublet of chemotherapy (fluoropyrimidine + platinum salt). For more than a decade, no obvious therapeutic progress has enriched the therapeutic arsenal for these patients, whether in the first-line with other anti-HER2 agents or in the context of trastuzumab resistance. The first results of studies based on trastuzumab deruxtecan and immune checkpoint inhibitors are therefore likely to change management practices for HER2+ EGAs.
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Adenis, Antoine
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Samalin, Emmanuelle
Relator term author
786 0# - DATA SOURCE ENTRY
Note Hépato-Gastro & Oncologie Digestive | 29 | 4 | 2022-04-01 | p. 507-513 | 2115-3310
856 41 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://shs.cairn.info/journal-hepato-gastro-oncologie-digestive-2022-4-page-507?lang=en&redirect-ssocas=7080">https://shs.cairn.info/journal-hepato-gastro-oncologie-digestive-2022-4-page-507?lang=en&redirect-ssocas=7080</a>

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