Dissecting cellulitis of the scalp treated by tumour necrosis factor inhibitors: a case series (notice n° 603198)

détails MARC
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fixed length control field 02054cam a2200277 4500500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250121154737.0
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Language code of text/sound track or separate title fre
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Authentication code dc
100 10 - MAIN ENTRY--PERSONAL NAME
Personal name Frechet, Laure
Relator term author
245 00 - TITLE STATEMENT
Title Dissecting cellulitis of the scalp treated by tumour necrosis factor inhibitors: a case series
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Date of publication, distribution, etc. 2021.<br/>
500 ## - GENERAL NOTE
General note 50
520 ## - SUMMARY, ETC.
Summary, etc. Background: Dissecting cellulitis of the scalp (DCS), also known as Hoffmann disease or perifolliculitis capitis abscedens et suffodiens, is a rare disease characterized by chronic inflammation of the scalp. Treatment is difficult and often disappointing. Objectives: To report our experience of TNF inhibitors in a series of patients with DCS. Materials & Methods: We conducted a monocentric retrospective study of nine patients with DCS treated with TNF blocker after failure of other conventional treatments. Results: After a mean duration of treatment by TNF inhibitors of 17 ± 16 months, four patients (44% versus 0%) had a Physician's Global Assessment score of 0 or 1. We observed a 67% reduction in the number of inflammatory nodules, an 88% reduction in purulent drainage and a 45% improvement in Dermatology Life Quality Index. The mean treatment satisfaction index was 6.6 ± 1.6 out of 10. Conclusion: Our study suggests that TNF inhibitors are effective against disease activity and may improve quality of life in the management of DCS refractory to conventional treatments.
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element infliximab
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element adalimumab
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element issecting cellulitis of the scalp
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Puzenat, Eve
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Charollais, Romain
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Dresco, Flora
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Carlet, Clémentine
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Gallais-Serezal, Irène
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Nardin, Charlée
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Aubin, François
Relator term author
786 0# - DATA SOURCE ENTRY
Note European Journal of Dermatology | 31 | 1 | 2021-01-01 | p. 81-85 | 1167-1122
856 41 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://shs.cairn.info/revue-european-journal-of-dermatology-2021-1-page-81?lang=en&redirect-ssocas=7080">https://shs.cairn.info/revue-european-journal-of-dermatology-2021-1-page-81?lang=en&redirect-ssocas=7080</a>

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