Propranolol for the treatment of infantile hemangiomas: a nine-year monocentric experience from a tertiary hospital (notice n° 604685)

détails MARC
000 -LEADER
fixed length control field 02284cam a2200337 4500500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250121155424.0
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title fre
042 ## - AUTHENTICATION CODE
Authentication code dc
100 10 - MAIN ENTRY--PERSONAL NAME
Personal name Volonté, Martina
Relator term author
245 00 - TITLE STATEMENT
Title Propranolol for the treatment of infantile hemangiomas: a nine-year monocentric experience from a tertiary hospital
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Date of publication, distribution, etc. 2023.<br/>
500 ## - GENERAL NOTE
General note 58
520 ## - SUMMARY, ETC.
Summary, etc. Background. Propranolol is currently considered the first-line therapy for problematic infantile hemangiomas (IH), the most common benign vascular neoplasm of infancy. Objectives. We present a retrospective observational study aimed at assessing the efficacy of propranolol in 44 IH patients. Materials & Methods. A nine-year retrospective review considering clinicodemographical and therapy-related variables was performed on medical records of infants treated for IH with oral propranolol. Each lesion was assessed through a numeric severity score based on size and colour both at baseline and after treatment conclusion (p Results. Complete remission was achieved in 90.7% cases of IH with a general mean improvement in severity of 94.94%. No severe adverse effects were reported. Preterm patients showed a superior response compared to term infants, even though the difference was not significant (p=0.185). Conclusion. Propranolol showed high efficacy in terms of safety profile and cosmetic results. Prematurity and precocious therapy could be linked to a superior response.
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element systemic treatment
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element vascular neoplasms
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element infantile hemangiomas
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element Pediatric population
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element oral propranolol
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element hemangioma treatment
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Codazzi, Alessia Claudia
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Davidovich, Shay
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Apicella, Antonia
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Isoletta, Eugenio
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Barruscotti, Stefania
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Massa, Margherita
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name De Silvestri, Annalisa
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Marseglia, Gian Luigi
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Brazzelli, Valeria
Relator term author
786 0# - DATA SOURCE ENTRY
Note European Journal of Dermatology | 33 | 3 | 2023-05-01 | p. 265-269 | 1167-1122
856 41 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://shs.cairn.info/revue-european-journal-of-dermatology-2023-3-page-265?lang=en&redirect-ssocas=7080">https://shs.cairn.info/revue-european-journal-of-dermatology-2023-3-page-265?lang=en&redirect-ssocas=7080</a>

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