Which first-line treatment for cutaneous sarcoidosis? A retrospective study of 120 patients (notice n° 604883)

détails MARC
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fixed length control field 02834cam a2200445 4500500
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control field 20250121155501.0
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Language code of text/sound track or separate title fre
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100 10 - MAIN ENTRY--PERSONAL NAME
Personal name Cohen, Elisabeth
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245 00 - TITLE STATEMENT
Title Which first-line treatment for cutaneous sarcoidosis? A retrospective study of 120 patients
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Date of publication, distribution, etc. 2023.<br/>
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General note 58
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Summary, etc. BackgroundSarcoidosis is a systemic disease that affects the skin in about 25% of patients. The treatment of cutaneous sarcoidosis is guided by the extent of lesions, associated symptoms and organ involvement.ObjectivesTo evaluate rates of response to various potential first-line treatments for cutaneous sarcoidosis during the year following treatment initiation.Materials & MethodsThis retrospective multicentre study included 120 patients with cutaneous sarcoidosis. Treatment response was assessed retrospectively from the patients’ medical records. Univariate logistic regression analysis, with an estimation of unadjusted odds ratios (OR) and their 95% CI,was performed to identify factors associated with complete cutaneous remission (CR), followed by multivariate logistic regression analysis.ResultsAt one year, 43 of the 120 (36%) included patients had CR. The best response rates were obtained with oral corticosteroids (12/21, 57%), followed by a combination of hydroxychloroquine and topical steroids (6/13, 46%). In multivariate analysis, lupus pernio was the only predictor of a poor cutaneous response.ConclusionWe suggest the use of a combination of hydroxychloroquine and topical steroids as an optimal first-line treatment for cutaneous sarcoidosis, given the known adverse effects of systemic corticosteroids.
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Topical term or geographic name as entry element topical steroids
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Topical term or geographic name as entry element first-line treatment
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Topical term or geographic name as entry element systemic corticosteroids
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Topical term or geographic name as entry element hydroxychloroquine
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Topical term or geographic name as entry element cutaneous sarcoidosis
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element sarcoidosis
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Lheure, Coralie
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Ingen-
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Hotz, Claire
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Bettuzzi, Thomas
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Chasset, Francois
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Descamps, Vincent
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Deschamps, Lydia
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Mahevas, Matthieu
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Terrier, Benjamin
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Sohier, Pierre
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Guegan, Sarah
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Kramkimel, Nora
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700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Darbord, Delphine
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Chanal, Johan
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Oulès, Benedicte
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Aractingi, Selim
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Seta, Vannina
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Dupin, Nicolas
Relator term author
786 0# - DATA SOURCE ENTRY
Note European Journal of Dermatology | 33 | 6 | 2023-11-01 | p. 680-685 | 1167-1122
856 41 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://shs.cairn.info/revue-european-journal-of-dermatology-2023-6-page-680?lang=en&redirect-ssocas=7080">https://shs.cairn.info/revue-european-journal-of-dermatology-2023-6-page-680?lang=en&redirect-ssocas=7080</a>

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