Which first-line treatment for cutaneous sarcoidosis? A retrospective study of 120 patients (notice n° 604883)
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fixed length control field | 02834cam a2200445 4500500 |
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control field | 20250121155501.0 |
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Language code of text/sound track or separate title | fre |
042 ## - AUTHENTICATION CODE | |
Authentication code | dc |
100 10 - MAIN ENTRY--PERSONAL NAME | |
Personal name | Cohen, Elisabeth |
Relator term | author |
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Title | Which first-line treatment for cutaneous sarcoidosis? A retrospective study of 120 patients |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Date of publication, distribution, etc. | 2023.<br/> |
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General note | 58 |
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Summary, etc. | BackgroundSarcoidosis is a systemic disease that affects the skin in about 25% of patients. The treatment of cutaneous sarcoidosis is guided by the extent of lesions, associated symptoms and organ involvement.ObjectivesTo evaluate rates of response to various potential first-line treatments for cutaneous sarcoidosis during the year following treatment initiation.Materials & MethodsThis retrospective multicentre study included 120 patients with cutaneous sarcoidosis. Treatment response was assessed retrospectively from the patients’ medical records. Univariate logistic regression analysis, with an estimation of unadjusted odds ratios (OR) and their 95% CI,was performed to identify factors associated with complete cutaneous remission (CR), followed by multivariate logistic regression analysis.ResultsAt one year, 43 of the 120 (36%) included patients had CR. The best response rates were obtained with oral corticosteroids (12/21, 57%), followed by a combination of hydroxychloroquine and topical steroids (6/13, 46%). In multivariate analysis, lupus pernio was the only predictor of a poor cutaneous response.ConclusionWe suggest the use of a combination of hydroxychloroquine and topical steroids as an optimal first-line treatment for cutaneous sarcoidosis, given the known adverse effects of systemic corticosteroids. |
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Topical term or geographic name as entry element | topical steroids |
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
Topical term or geographic name as entry element | first-line treatment |
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
Topical term or geographic name as entry element | systemic corticosteroids |
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
Topical term or geographic name as entry element | hydroxychloroquine |
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
Topical term or geographic name as entry element | cutaneous sarcoidosis |
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
Topical term or geographic name as entry element | sarcoidosis |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Lheure, Coralie |
Relator term | author |
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Personal name | Ingen- |
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700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Hotz, Claire |
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700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Bettuzzi, Thomas |
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700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Chasset, Francois |
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700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Descamps, Vincent |
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700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Deschamps, Lydia |
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700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Mahevas, Matthieu |
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700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Terrier, Benjamin |
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700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Sohier, Pierre |
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700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Guegan, Sarah |
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700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Kramkimel, Nora |
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700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Darbord, Delphine |
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700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Chanal, Johan |
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700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Oulès, Benedicte |
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700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Aractingi, Selim |
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700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Seta, Vannina |
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700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Dupin, Nicolas |
Relator term | author |
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Note | European Journal of Dermatology | 33 | 6 | 2023-11-01 | p. 680-685 | 1167-1122 |
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Uniform Resource Identifier | <a href="https://shs.cairn.info/revue-european-journal-of-dermatology-2023-6-page-680?lang=en&redirect-ssocas=7080">https://shs.cairn.info/revue-european-journal-of-dermatology-2023-6-page-680?lang=en&redirect-ssocas=7080</a> |
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