Electrical Wada for pre-surgical memory testing: a case report (notice n° 612155)
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fixed length control field | 02389cam a2200325 4500500 |
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control field | 20250121162739.0 |
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Language code of text/sound track or separate title | fre |
042 ## - AUTHENTICATION CODE | |
Authentication code | dc |
100 10 - MAIN ENTRY--PERSONAL NAME | |
Personal name | Kaestner, Erik |
Relator term | author |
245 00 - TITLE STATEMENT | |
Title | Electrical Wada for pre-surgical memory testing: a case report |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Date of publication, distribution, etc. | 2022.<br/> |
500 ## - GENERAL NOTE | |
General note | 48 |
520 ## - SUMMARY, ETC. | |
Summary, etc. | We report a case study of a surgical candidate, a 51-year-old woman with left temporal lobe epilepsy, who failed a left injection intracarotid amobarbital procedure (e.g., Wada test), scoring 0 of 8 items. This raised concerns for postoperative memory decline. However, the patient was uninterested in a neuromodulatory approach and wished to be reconsidered for surgery. A stereotactic laser amygdalohippocampotomy (SLAH) was considered, encouraging the need for an alternative test to evaluate risk of memory decline. We developed a novel approach to testing memory during stimulation of a depth electrode implanted in the hippocampus, i.e., an electric Wada. During multiple stimulation trials across a range of amplitudes, the patient scored up to 8 of 8 items, which suggested strong contralateral memory support. The surgical team proceeded with a radiofrequency ablation and a subsequent SLAH. The patient remains seizure-free at 12 months post SLAH with no evidence of verbal or visuospatial memory decline based on a post-surgical neuropsychological battery. We believe that this case study provides a proof of concept for the feasibility and possible utility of an electric version of the Wada procedure. Future studies are needed to develop an optimal paradigm and to validate this approach. |
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
Topical term or geographic name as entry element | intracarotid amobarbital procedure |
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
Topical term or geographic name as entry element | electric Wada |
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
Topical term or geographic name as entry element | Wada test |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Pedersen, Nigel P. |
Relator term | author |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Hu, Ranling |
Relator term | author |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Vosoughi, Armin |
Relator term | author |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Alwaki, Abdulrahman |
Relator term | author |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Ruiz, Andres Rodriguez |
Relator term | author |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Staikova, Ekaterina |
Relator term | author |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Hewitt, Kelsey C. |
Relator term | author |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Epstein, Charles |
Relator term | author |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | McDonald, Carrie R. |
Relator term | author |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Gross, Robert E. |
Relator term | author |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Drane, Daniel L. |
Relator term | author |
786 0# - DATA SOURCE ENTRY | |
Note | Epileptic Disorders | Vol 24 | 2 | 2022-02-01 | p. 411-416 | 1294-9361 |
856 41 - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | <a href="https://shs.cairn.info/revue-epileptic-disorders-2022-2-page-411?lang=en&redirect-ssocas=7080">https://shs.cairn.info/revue-epileptic-disorders-2022-2-page-411?lang=en&redirect-ssocas=7080</a> |
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