Neurodéveloppement et polluants environnementaux (notice n° 614958)
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| fixed length control field | 04296cam a2200325 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250121163832.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Jeanne, Etiemble |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Neurodéveloppement et polluants environnementaux |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2022.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 72 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Le développement du cerveau humain consiste en une série de processus spatiotemporels complexes. Le neurodéveloppement est le processus de développement des neurones (incluant la prolifération, la migration, la différenciation, la synaptogenèse, l’apoptose, la gliogenèse, la myélinisation) qui s’étend principalement de la période embryonnaire à l’adolescence. Des modifications de l’environnement, notamment in utero, peuvent générer des altérations irréversibles du neurodéveloppement. Au même titre que les infections, le stress ou les carences nutritionnelles de la mère, l’exposition aux polluants chimiques environnementaux est suspectée d’être impliquée dans les perturbations du neurodéveloppement possiblement responsables d’atteintes sensorimotrices, cognitives ou comportementales et de l’incidence croissante des troubles cliniques du neurodéveloppement (tels que les troubles du spectre autistique [TSA] et le trouble déficit de l’attention/hyperactivité [TDAH]) chez les enfants. Selon l’ensemble des études épidémiologiques longitudinales, certaines substances chimiques relativement récentes et d’autres plus anciennes (métaux toxiques, polluants organiques persistants, pesticides, bisphénols, phtalates, particules fines provenant de la pollution atmosphérique, etc.) sont associées aux perturbations et troubles du neurodéveloppement. Les effets observés en épidémiologie sont compatibles avec les mécanismes d’action de ces substances chimiques sur le neurodéveloppement. Les mesures de biomarqueurs des substances chimiques chez les femmes enceintes et les enfants récemment réalisées en France et en Europe attestent d’une exposition réelle à ces substances pendant les périodes de vulnérabilité neurodéveloppementale et du risque potentiel associé. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Neurodevelopment is the process of the development of neurons: their proliferation, migration, differentiation, synaptogenesis, apoptosis, gliogenesis and myelination. It extends from the embryonic period through adolescence. Environmental changes particularly in utero, can lead to irreversible neurodevelopmental alterations. Exposure to environmental chemical pollutants, as to maternal infections, stress and nutritional deficiencies, has been suspected of involvement in neurodevelopmental disturbances responsible for sensorimotor, cognitive or behavioural impairment and for the increasing incidence of clinical neurodevelopmental disorders (such as autism spectrum disorders and attention deficit/hyperactivity disorder) in children. According to the longitudinal epidemiological studies, some chemicals of relatively recent concern, as well as older chemicals (toxic metals, persistent organic pollutants, pesticides, bisphenols, phthalates, and fine particles from air pollution), are associated with neurodevelopmental disorders. The effects observed in epidemiology are consistent with the mechanisms of action of these chemicals on neurodevelopment. Biomarker measurements of chemicals in pregnant women and children recently carried out in France and Europe attest to exposure to these substances during periods of neurodevelopmental vulnerability and to the potential risk associated with it. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | femmes enceintes et enfants |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | données épidémiologiques |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | troubles du neurodéveloppement |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | neurodéveloppement |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | mécanismes |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | polluants environnementaux |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | pregnant women and children |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | epidemiological data |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | neurodevelopment |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | mechanisms |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | neurodevelopmental disorders |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | environmental pollutants |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cordier, Sylvaine |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Environnement, Risques & Santé | 21 | 1 | 2022-02-09 | p. 13-22 | 1635-0421 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://shs.cairn.info/revue-environnement-risques-et-sante-2022-1-page-13?lang=fr&redirect-ssocas=7080">https://shs.cairn.info/revue-environnement-risques-et-sante-2022-1-page-13?lang=fr&redirect-ssocas=7080</a> |
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