Les hépatites médicamenteuses (notice n° 664881)
[ vue normale ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02685cam a2200277 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250121193801.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Meunier, Lucy |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Les hépatites médicamenteuses |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2022.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 35 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Drug-induced liver injury is one of the most common causes of hepatitis but also one of the most difficult to diagnose. These difficulties are due to the plethora of drugs used in clinical practice, herbs and dietary supplements with hepatotoxic potential, the presentation by various clinical and pathological phenotypes and the current lack of specific biomarkers.The diagnosis of drug-induced liver injury is based on a combination of evidence and the elimination of differential diagnoses. For idiosyncratic hepatitis, the mechanisms of toxicity are often partially known and no effective therapy has been found. In contrast, paracetamol toxicity is direct and dose-dependent and N-acetyl cysteine has been shown to be effective in these cases. This review aims to provide an update on the diagnosis, treatment and mechanism of drug-induced hepatitis. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Les hépatites médicamenteuses sont une des causes d’hépatites les plus fréquentes mais également parmi les plus difficiles à diagnostiquer. Ces difficultés s’expliquent par la pléthore de médicaments utilisés dans la pratique clinique, des plantes et de compléments alimentaires ayant un potentiel hépatotoxique, la présentation par divers phénotypes cliniques et pathologiques, et l’absence actuelle de biomarqueurs spécifiques.Le diagnostic d’hépatite médicamenteuse repose sur un faisceau d’arguments et l’élimination des diagnostics différentiels. Pour les hépatites idiosyncrasiques, les mécanismes de toxicité sont souvent partiellement connus et aucune thérapeutique efficace n’a été découverte. En revanche, pour le paracétamol, la toxicité est directe, dose dépendante et le N-acétylcystéine a montré son efficacité. Cette revue se propose de faire le point sur le diagnostic, le traitement et le mécanisme des hépatites médicamenteuses. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | hépatite médicamenteuse |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | toxicité |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | médicament |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | drug-induced hepatitis |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | toxicity |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | hepatitis |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Louvet, Alexandre |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Malezieux, Émilie |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Larrey, Dominique |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Hépato-Gastro & Oncologie Digestive | 29 | 1 | 2022-01-01 | p. 77-87 | 2115-3310 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://shs.cairn.info/revue-hepato-gastro-et-oncologie-digestive-2022-1-page-77?lang=fr&redirect-ssocas=7080">https://shs.cairn.info/revue-hepato-gastro-et-oncologie-digestive-2022-1-page-77?lang=fr&redirect-ssocas=7080</a> |
Pas d'exemplaire disponible.
Réseaux sociaux