Cholangites : du diagnostic au traitement (notice n° 666599)
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| fixed length control field | 04067cam a2200397 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250121194303.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Chagneau, Carine |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Cholangites : du diagnostic au traitement |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2024.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 8 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The diagnosis of cholangitis should be made in the presence of chronic cholestasis, after ruling out chronic viral hepatitis, medication and with normal hepatic ultrasound. The clinical signs of cholangitis are not specific: asthenia, pruritus. Anti-mitochondrial antibody (AMA) testing is the first key step in diagnosis. When positive, the diagnosis is primary biliary cholangitis (PBC). This is a destructive autoimmune disease of the small bile ducts, mainly affecting women around the age of 50. First-line treatment with ursodesoxycholic acid (AUDC) slows the progression to cirrhosis and its complications. When anti-mitochondrial antibodies are negative, cholangio-MRI is recommended to identify bile ducts strictures, which may suggest the diagnosis of primary sclerosing cholangitis (PSC). This inflammatory disease of the large bile ducts tends to affect men aged around 40, and is very frequently associated with IBD. Treatment of PSC is also based on AUDC. Complications of PSC include angiocholitis, cholangiocarcinoma and cirrhosis, with the risk of decompensation. When associate with IBD, there is also an increased risk of colon cancer, justifying annual imaging surveillance of the bile ducts and also annual surveillance of the colon. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Le diagnostic de cholangite doit être évoqué devant une cholestase chronique après avoir éliminé une hépatite virale chronique, une prise médicamenteuse et en cas d'échographie hépatique normale. Les signes cliniques de cholangite sont peu spécifiques: asthénie, prurit. Le dosage des anticorps anti-mitochondries (AMA) est la première étape-clé du diagnostic. Lorsqu'ils sont positifs, le diagnostic de cholangite biliaire primitive (CBP) est retenu. Il s'agit d'une atteinte destructrice auto-immune des petits canaux biliaires touchant principalement la femme aux alentours de 50 ans. Le traitement de première ligne par acide ursodésoxycholique (AUDC) permet de ralentir l'évolution vers la cirrhose et ses complications. Lorsque les anticorps anti-mitochondries sont négatifs, il est alors recommandé de réaliser une cholangio-IRM, afin de chercher des sténoses étagées des voies biliaires permettant d'évoquer le diagnostic de cholangite sclérosante primitive (CSP). Cette maladie inflammatoire des grosses voies biliaires touche plutôt les hommes aux alentours de 40 ans et est très fréquemment associée à une MICI. Le traitement de la CSP repose également sur l'AUDC. Les complications de la CSP sont les angiocholites, le cholangiocarcinome et la cirrhose avec le risque de décompensation. En cas d'association à une MICI, il existe également un surrisque de cancer du côlon justifiant une surveillance annuelle des voies biliaires par imagerie et une surveillance annuelle du côlon par coloscopie. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | cholangite |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | surveillance du côlon |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | maladie inflammatoire des voies biliaires |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | cholangite |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | surveillance du côlon |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | maladie inflammatoire des voies biliaires |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | cholangite |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | surveillance du côlon |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | maladie inflammatoire des voies biliaires |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | cholangitis |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | colon surveillance |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | inflammatory biliary disease |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | cholangitis |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | colon surveillance |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | inflammatory biliary disease |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | cholangitis |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | colon surveillance |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | inflammatory biliary disease |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rosa, Isabelle |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Hépato-Gastro & Oncologie Digestive | 31 | 8 | 2024-10-02 | p. 845-855 | 2115-3310 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://shs.cairn.info/revue-hepato-gastro-et-oncologie-digestive-2024-8-page-845?lang=fr&redirect-ssocas=7080">https://shs.cairn.info/revue-hepato-gastro-et-oncologie-digestive-2024-8-page-845?lang=fr&redirect-ssocas=7080</a> |
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