Magnesium citrate supplementation decreased blood pressure and HbA1c in normomagnesemic subjects with metabolic syndrome: a 12-week, placebo-controlled, double-blinded pilot trial (notice n° 755421)

détails MARC
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control field 20250123095926.0
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Language code of text/sound track or separate title fre
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Authentication code dc
100 10 - MAIN ENTRY--PERSONAL NAME
Personal name Afitska, Kseniia
Relator term author
245 00 - TITLE STATEMENT
Title Magnesium citrate supplementation decreased blood pressure and HbA1c in normomagnesemic subjects with metabolic syndrome: a 12-week, placebo-controlled, double-blinded pilot trial
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Date of publication, distribution, etc. 2021.<br/>
500 ## - GENERAL NOTE
General note 82
520 ## - SUMMARY, ETC.
Summary, etc. Magnesium (Mg) supplementation was shown to improve metabolic syndrome (MetS) parameters in hypomagnesemic patients. The current study evaluated the role of Mg in normomagnesemic individuals with MetS. Patients were randomly assigned to 400 mg Mg as Mg citrate or placebo daily for 12 weeks. Blood pressure (BP), HbA1c, plasma concentrations of glucose, Mg and Ca, blood-ionized Mg, serum concentrations of cholesterol, triglycerides, vitamin D, creatinine, interleukin-6, and C-reactive protein were measured at baseline and after 12 weeks. Data were obtained from n = 13 in the Mg supplemented and n = 11 in the placebo group. Mg supplementation led to a significant increase in plasma Mg concentration (0.78 ± 0.07 mmol/L to 0.83 ± 0.07 mmol/L) and a decrease in systolic and diastolic BP (baseline: 145 ± 10/85 ± 3 mmHg; 12 weeks: 121 ± 5/79 ± 3 mmHg). HbA1c decreased significantly in the Mg group (6.43 ± 0.64% to 6.15 ± 0.55%), and the difference in change between placebo and Mg group was significant. Serum vitamin D levels significantly increased only in the Mg group. In normomagnesemic individuals with MetS, oral Mg citrate supplementation reduced HbA1c and BP.
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element blood pressure
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element oral supplementation
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element magnesium citrate
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element glycemic control
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element metabolic syndrome
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Clavel, Julia
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Kisters, Klaus
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Vormann, Jürgen
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Werner, Tanja
Relator term author
786 0# - DATA SOURCE ENTRY
Note Magnesium Research | 34 | 3 | 2021-07-01 | p. 130-139 | 0953-1424
856 41 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://shs.cairn.info/revue-magnesium-research-2021-3-page-130?lang=en&redirect-ssocas=7080">https://shs.cairn.info/revue-magnesium-research-2021-3-page-130?lang=en&redirect-ssocas=7080</a>

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