The association between abnormal serum magnesium levels and prognosis of elderly patients with community-acquired pneumonia (notice n° 755425)

détails MARC
000 -LEADER
fixed length control field 03235cam a2200277 4500500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250123095927.0
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title fre
042 ## - AUTHENTICATION CODE
Authentication code dc
100 10 - MAIN ENTRY--PERSONAL NAME
Personal name Wang, Si-Qiong
Relator term author
245 00 - TITLE STATEMENT
Title The association between abnormal serum magnesium levels and prognosis of elderly patients with community-acquired pneumonia
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Date of publication, distribution, etc. 2021.<br/>
500 ## - GENERAL NOTE
General note 86
520 ## - SUMMARY, ETC.
Summary, etc. Objective: To investigate the association between abnormal serum magnesium levels and the prognosis of elderly patients with community-acquired pneumonia (CAP). Methods: A retrospective study was conducted on 1381 elderly patients with CAP in the First Hospital of Qinhuangdao between January 2015 and December 2018. Serum magnesium concentrations in the range of 0.75–1.25 mmol/L were defined as normal. Patients were assigned into normal, hypomagnesemia, and hypermagnesemia groups. The primary outcome was in-hospital mortality, indicating whether a patient died at the time of discharge from the hospital. Results: The percentages of respiratory failure and mechanical ventilation were 18.6% and 10.6 % in the normal group, 29% and 16.5 % in the hypomagnesemia, and 42.9% and 35.7% in the hypermagnesemia groups. The occurrence of shock was 8.5% and 4.5% in the hypomagnesemia group and the normal group. The percentages of the length of stay at ICU were 14.9%, 18.8%, and 57.1% in the hypomagnesemia, normal, and hypermagnesemia groups. The in-hospital mortality rate was 5.3%, 9.1%, and 35.7% in the normal, hypomagnesemia, and hypermagnesemia groups, respectively. The results of univariate analysis showed that the in-hospital mortality in the hypomagnesemia group was 1.790 (95% confidence interval (CI): 1.009∼3.176, P=0.046) times higher than that in the normal group; in the hypermagnesemia group, it was 9.947 (95% CI: 3.238–30.556, P&lt;0.001) times higher than that in the normal group. The results of multivariate logistic regression analysis showed that after adjusting for gender, age, diabetes, heart failure, cerebrovascular disease, cancer, estimated glomerular filtration rate (eGFR), glucose, and CURB-65 score, in the hypomagnesemia group, the in-hospital mortality was 1.746 (95% confidence interval (CI): 0.956∼3.186, P=0.070) times higher than that in the normal group, and 5.689 (95% CI: 1.583–20.446, P=0.008) times higher in the hypermagnesemia group than that in the normal group. Conclusion: Abnormal serum magnesium levels are strongly associated with in-hospital mortality in elderly patients with CAP. The measurement of serum magnesium levels in elderly patients with CAP at admission may assist clinicians to determine the prognosis of such patients.
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element prognosis
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element serum magnesium level
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element elderly patients
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element in-hospital mortality
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN)
Topical term or geographic name as entry element community-acquired pneumonia
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Lu, Dong-Xi
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Zhang, Jian-Dong
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Wang, Zhi-Wei
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Li, Xiao-Wei
Relator term author
700 10 - ADDED ENTRY--PERSONAL NAME
Personal name Ma, Chun-Ming
Relator term author
786 0# - DATA SOURCE ENTRY
Note Magnesium Research | 34 | 4 | 2021-10-01 | p. 159-165 | 0953-1424
856 41 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://shs.cairn.info/revue-magnesium-research-2021-4-page-159?lang=en&redirect-ssocas=7080">https://shs.cairn.info/revue-magnesium-research-2021-4-page-159?lang=en&redirect-ssocas=7080</a>

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