Estimation du débit de filtration glomérulaire de l’enfant : intérêt de la formule FAS (notice n° 760741)
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| fixed length control field | 03594cam a2200325 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250123102359.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Ratouit, Pauline |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Estimation du débit de filtration glomérulaire de l’enfant : intérêt de la formule FAS |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2023.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 10 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | L’équation recommandée pour estimer le débit de filtration glomérulaire (DFG) chez l’enfant est la formule de Schwartz mise à jour en 2009. Cependant, celle-ci n’est pas toujours utilisée en routine, car elle fait intervenir la taille, un paramètre auquel les laboratoires, notamment hospitaliers, n’ont pas facilement accès. La formule FAS ( Full Aged Spectrum), mise au point par un groupe européen, permet de s’affranchir de la taille de l’enfant. Nous avons comparé les résultats du DFG obtenus à partir des équations CKD-EPI ( Chronic Kidney Disease-EPIdemiology collaboration) et FAS, aux valeurs obtenues avec la formule de Schwartz. Nous avons réalisé une étude rétrospective sur 1 668 enfants âgés entre 2 et 14 ans dont le dosage de la créatininémie avait été effectué durant l’hospitalisation. Nous avons montré que l’équation FAS est bien corrélée à celle de Schwartz (r = 0,88), avec une sous-estimation moyenne du DFG de 6,2 % versus CKD-EPI qui a un coefficient de corrélation égal à 0,45 et qui surestime le DFG d’environ 42 % par rapport à la formule de Schwartz. De plus, la concordance à 30 % est de 99 % pour FAS alors qu’elle n’est que de 35 % pour CKD-EPI. Ainsi, nous recommandons d’utiliser l’équation FAS pour estimer le DFG chez l’enfant entre 2 et 14 ans lorsque la taille n’est pas disponible. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The recommended equation to estimate the value of glomerular filtration rate (eGFR) among children is Schwartz equation updated in 2009. However, it is few frequently used because involves height, a factor rarely documented for laboratories, especially hospital laboratories. The FAS (Full Aged Spectrum) formula developed by a European group, allows to get away from this factor. We compared CKD-EPI (Chronic Kidney Disease-EPIdemiology collaboration) and FAS formulas to Schwartz equation to estimate GFR in children. We realized a retrospective study included 1.668 children between 2 and 14 years old, whose serum creatinine had been measured during their hospitalization stay. We showed that FAS formula is correlated to Schwartz (r = 0.88), with a mean underestimation of eGFR at 6.2% versus CKD-EPI which has a correlation coefficient equal to 0.45 and overestimates eGFR to approximatively 42.0% compared to Schwartz formula. Furthermore, concordance at 30% is 99% with FAS whereas it’s only 35% with CKD-EPI. Thus, we recommend using the FAS formula to estimate GFR in children between 2 and 14 years old when their height is not available. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | maladie rénale chronique |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | débit de filtration glomérulaire |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | équation Schwartz |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | équation FAS |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | enfant |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | glomerular filtration rate |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | FAS equation |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | chronic kidney disease |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | children |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Schwartz equation |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Harambat, Jérôme |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bérard, Annie M. |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lacape, Geneviève |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Néphrologie & Thérapeutique | Volume 19 | 1 | 2023-01-26 | p. 35-43 | 1769-7255 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://shs.cairn.info/revue-nephrologie-et-therapeutique-2023-1-page-35?lang=fr&redirect-ssocas=7080">https://shs.cairn.info/revue-nephrologie-et-therapeutique-2023-1-page-35?lang=fr&redirect-ssocas=7080</a> |
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