Étude toxicologique et activité psychotrope des huiles essentielles de Laurus nobilis et de Vitex agnus-castus (notice n° 782859)
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| fixed length control field | 02966cam a2200373 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250123112851.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Labiad, H. |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Étude toxicologique et activité psychotrope des huiles essentielles de Laurus nobilis et de Vitex agnus-castus |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2019.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 38 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This study aims in the valorisation of the essential oils obtained from Laurus nobilis and Vitex agnus-castus through their acute toxicological validation and sedative activity. The results of the study of toxicity show that the lethal dose 50 of the two oils is higher than 5 g/kg. This implies that the essential oils could be classified in the category 5 according to the guideline of the OCDE 423. Consequently, Laurus nobilis and Vitex agnus-castus could be considered as non-toxic. The results of the test Rotarod, the hole board, and the white/obscure room demonstrate that Laurus nobilis and Vitex agnus-castus exercise oils exhibited a sedative effect in the mouse. These results suggest that Laurus nobilis and Vitex agnus-castus could make a good alternative of the synthetic sedative agents used in the pharmaceutical industry. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Le présent travail s'inscrit dans le cadre de la valorisation des huiles essentielles de Laurus nobilis et de Vitex agnus-castus à travers l'étude de la toxicité orale aiguë et l'évaluation de l'activité sédative. Les résultats de l'étude de la toxicité font ressortir que la dose létale 50 des deux espèces est supérieure à 5 g/kg, ce qui implique que les deux plantes peuvent être classées dans la catégorie 5 selon le guideline de l'OCDE 423. En conséquence, Laurus nobilis et Vitex agnus-castus peuvent être considérées non toxiques. Les résultats des tests de Rota-Rod, de la planche à trous et de la chambre blanche/obscure ont démontré que les huiles essentielles de Laurus nobilis et de Vitex agnus-castus exercent un effet sédatif considérable chez la souris. Ces résultats suggèrent que Laurus nobilis et Vitex agnus-castus pourraient constituer une bonne alternative aux sédatifs de synthèse utilisés en industrie pharmaceutique. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Activité sédative |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Toxicité aiguë |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Laurus nobilis |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Huile essentielle |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Vitex agnus-castus |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Acute toxicity |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Laurus nobilis |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Vitex agnus-castus |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Essential oil |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Seductive activity |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | El Jemli, M. |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Imer, Mathilde |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ach, Claudine |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ghanmi, M. |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Satrani, B. |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Al-Haj, Yousra |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Fadli, M. |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Phytothérapie | 17 | 5 | 2019-10-01 | p. 276-282 | 1624-8597 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://shs.cairn.info/revue-phytotherapie-2019-5-page-276?lang=fr&redirect-ssocas=7080">https://shs.cairn.info/revue-phytotherapie-2019-5-page-276?lang=fr&redirect-ssocas=7080</a> |
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