Effects of Dietary Microalgae Nannochloropsis gaditana on Serum and Redox Status in Obese Rats Subjected to a High Fat Diet (notice n° 782873)
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| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250123112852.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Bendaoud, A. |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Effects of Dietary Microalgae Nannochloropsis gaditana on Serum and Redox Status in Obese Rats Subjected to a High Fat Diet |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2019.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 45 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Marine organisms, including microalgae, are among major subjects of investigation for the research of new molecules with biological activity that may improve responses to metabolic treatment. Microalgae Nannochloropsis gaditana are rich sources of diverse bioactive compounds. In this context, the present study was conducted to evaluate the effects of dietary microalgae Nannochloropsis gaditana in the modulation of biochemical parameters and oxidant/antioxidant markers in rats subjected to a high fat diet. Male rats were fed on control or high fat diet (hyperlipidic/hypercaloric diet), supplemented or not with Nannochloropsis gaditana (10%) for two months. At the end of the experiment, plasma and tissues biochemical parameters and oxidant/antioxidant markers were determined. Our results show that the high fat diet induced a significant increase in body weight, food intake, and adverse alterations in biochemical parameters such as an increase in plasma glucose, triglyceride, cholesterol, and oxidant markers. Nannochloropsis gaditana supplementation in high fat diet induced a reduction in weight gain, plasma, and tissue lipids and attenuates oxidative stress, thus, improving the metabolic status. In conclusion, Nannochloropsis gaditana by the properties of their bioactive compounds seem to have a hypoglycemic, hypolipidemic nature and improves the redox status of the subject, which could prevent and/or attenuate some metabolic disorders associated with obesity. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Les organismes marins, dont les microalgues, constituent un champ d'investigation majeur pour la recherche de nouvelles molécules à activité biologique susceptibles d'améliorer les réponses aux traitements métaboliques. Les microalgues Nannochloropsis gaditana sont des sources riches en divers composés bioactifs. Dans ce contexte, nous avons évalué les effets des microalgues Nannochloropsis gaditana dans la modulation des paramètres biochimiques et des marqueurs oxydants/antioxydants chez le rat soumis à un régime hyperlipidique. Les rats mâles reçoivent pendant deux mois le régime standard témoin ou le régime hyperlipidique (régime hyperlipidique/hypercalorique) supplémenté ou non de Nannochloropsis gaditana (10 %). À la fin de l'expérimentation, les paramètres biochimiques et les marqueurs oxydants/antioxydants plasmatiques et tissulaires sont déterminés. Nos résultats montrent que le régime hyperlipidique induit une augmentation significative du poids corporel, de la prise alimentaire et des altérations indésirables des paramètres biochimiques par augmentation des teneurs plasmatiques en glucose, des triglycérides, du cholestérol et des marqueurs du stress oxydatif. La supplémentation en microalgues Nannochloropsis gaditana dans le régime hyperlipidique induit une réduction du gain de poids, des lipides plasmatiques et tissulaires et atténue le stress oxydatif et améliore ainsi le statut métabolique. En conclusion, les Nannochloropsis gaditana par leur richesse en composés bioactifs semblent avoir des propriétés hypoglycémiante, hypolipédémiante et améliorent le statut redox qui pourrait prévenir et/ou atténuer certains désordres métaboliques associés à l'obésité. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Obésité |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Microalgue |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Métabolisme |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Nannochloropsis gaditana |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Régime hyperlipidique |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Stress oxydatif |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | High fat diet |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Nannochloropsis gaditana |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Obesity |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Metabolism |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Microalgae |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Oxidative stress |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed, F.Z. Baba |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Merzouk, H. |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bouanane, S. |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bendimerad, S. |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Phytothérapie | 17 | 4 | 2019-08-01 | p. 177-187 | 1624-8597 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://shs.cairn.info/revue-phytotherapie-2019-4-page-177?lang=en&redirect-ssocas=7080">https://shs.cairn.info/revue-phytotherapie-2019-4-page-177?lang=en&redirect-ssocas=7080</a> |
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