Pouvoir antimicrobien des extraits de l’Atriplex halimus contre l’agent pathogène Vibrio cholerae (notice n° 782964)
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| fixed length control field | 04337cam a2200421 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250123112904.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Hamdi, A. |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Pouvoir antimicrobien des extraits de l’Atriplex halimus contre l’agent pathogène Vibrio cholerae |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2024.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 87 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The bacterial genus Vibrio is one of the ubiquitous bacteria in coastal areas and waters. Among its strains Vibrio cholerae which is recognized for its clinical, health, and economic impact. The spread of multi-drug resistant clones is a threat to public health. The aim of this study was to search for Vibrio cholerae in water and then valorize a medicinal plant, Atriplex halimus, by testing the antibacterial effect of these extracts on the isolates of Vibrio cholerae detected. Water samples from different sites in Mascara (Algeria) were taken. Vibrio cholerae strains were identified after isolation by biochemical testing and serotyping. Antibiotic resistance was determined by an antibiogram, and the antimicrobial potency of extracts of the medicinal plant Atriplex halimus was tested by the method of diffusion on agar and microdilution in liquid medium. The first results bring to light the presence of Vibrio cholerae in the water sampled. These strains were multiresistant to most antibiotics, especially ampicillin, tetracycline, amoxicillin, erythromycin, and doxycycline. The two extracts of the plant have antibacterial activity against Vibrio cholerae. The aqueous extract has an inhibitory effect with a content of 100 to 200 μg/ml while the methanolic extract displays lower concentrations of the order of 25 to 100 μg/ml. These results encourage the identification of bioactive substances capable of restoring the activity of several classes of synthetic antibiotics on these multiresistant strains. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Le genre bactérien Vibrio fait partie des bactéries ubiquistes des eaux et des zones côtières, certaines espèces sont pathogènes pour l’homme et les animaux aquatiques. Parmi elles, Vibrio cholerae est reconnue pour son impact clinique, sanitaire et économique. La propagation de clones multirésistants aux antibiotiques est une menace pour la santé publique. Dans ce travail, notre objectif est d’évaluer le risque de contamination des eaux de différents sites de la ville de Mascara (Algérie) par vibrion cholérique, de déterminer sa résistance aux antibiotiques et de rechercher de nouveaux composés alternatifs naturels actifs issus de la plante médicinale Atriplex halimus, sur cet agent pathogène. Les premiers résultats révèlent la présence de Vibrio cholerae dans les eaux prélevées. Ces souches étaient multirésistantes à la plupart des antibiotiques surtout à l’ampicilline, à la tétracycline, à l’amoxicilline, à l’érythromycine et à la doxycycline. Les extraits aqueux et méthanolique de la plante possèdent une activité antibactérienne contre Vibrio cholerae. L’extrait aqueux exerce un effet inhibiteur avec une teneur de 100 à 200 μl/ml, alors que l’extrait méthanolique est actif avec des concentrations plus faibles de l’ordre de 25 à 100 μl/ml. Ces résultats encouragent la conduite à l’identification de substances bioactives, capables de restaurer l’activité de plusieurs classes d’antibiotiques synthétiques sur ces souches multirésistantes. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Atriplex halimus |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Effet antibactérien |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Vibrio cholerae |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Composés phénoliques |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Substance bioactive |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Atriplex halimus |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Effet antibactérien |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Vibrio cholerae |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Composés phénoliques |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Substance bioactive |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Atriplex halimus |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Vibrio cholerae |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Phenolic compound |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Antibacterial effect |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Bioactive substance |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Atriplex halimus |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Vibrio cholerae |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Phenolic compound |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Antibacterial effect |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Bioactive substance |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Autret, Alain |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Phytothérapie | 22 | 1 | 2024-01-01 | p. 4-12 | 1624-8597 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://shs.cairn.info/revue-phytotherapie-2024-1-page-4?lang=fr&redirect-ssocas=7080">https://shs.cairn.info/revue-phytotherapie-2024-1-page-4?lang=fr&redirect-ssocas=7080</a> |
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