Analyses phytochimiques et détermination de l’activité antiarthritique in vitro des extraits de graines de Linum usitatissimum L. (notice n° 783066)
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| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250123112933.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Cheurfa, M. |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Analyses phytochimiques et détermination de l’activité antiarthritique in vitro des extraits de graines de Linum usitatissimum L. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2024.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 89 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The objective of this study is to determine the antiarthritic activity of the aqueous and hydroalcoholic extracts of Linum usitatissimum L. seeds in vitro, as well as the phytochemical screening and determination of the flavonoid and flavonol content in the extracts. Phytochemical analysis of Linum usitatissimum seeds revealed the presence of sterols, tannins, flavonoids, phenols, and alkaloids in the aqueous and hydroalcoholic extracts. The flavonoid contents were 06.91 ± 0.38 and 04.85 ± 0.05 mg QE/g extract for the hydroalcoholic and aqueous extracts, respectively. For the flavonol assay, the contents are 04.53 ± 0.25 mg QE/g for the hydroalcoholic extract and 04.51 ± 0.03 mg QE/g for the aqueous extract. With the Bovin Serum Albumin (BSA) test, the aqueous extract showed the protective activity against BSA denaturation significantly (P < 0.05) the highest with an IC50 of 07.62 ± 1.56 mg/ml; on the other hand, the hydroalcoholic extract of Linum usitatissimum seeds is revealed significantly (P < 0.05) the most active with the egg albumin denaturation test whose IC50 recorded is 36.86 ± 2.72 mg/ml. From the results obtained, it was found that the aqueous and hydroalcoholic extracts of Linum usitatissimum seeds possess protective activity in vitro against protein denaturation, which plays a role in the training of inflammatory and arthritic diseases. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | L’objectif de cette étude est la détermination de l’activité antiarthritique in vitro des extraits aqueux et hydroalcoolique des graines de Linum usitatissimum L. ainsi que le criblage phytochimique, le dosage des flavonoïdes et des flavonols de ces extraits. Les analyses photochimiques des graines de Linum usitatissimum ont révélé la présence des stérols, tanins, flavonoïdes, phénols et les alcaloïdes dans les extraits aqueux et hydroalcoolique. Les teneurs en flavonoïdes sont de 6,91 ± 0,38 et 4,85 ± 0,05 mg EQ/g d’extrait pour l’extrait hydroalcoolique et l’extrait aqueux respectivement. Pour le dosage des flavonols, les teneurs sont de 4,53 ± 0,25 mg EQ/g pour l’extrait hydroalcoolique et de 4,51 ± 0,03 pour l’extrait aqueux. Avec le test de BSA (bovine serum albumin), l’extrait aqueux a montré l’activité protectrice contre la dénaturation de BSA significativement (p < 0,05) la plus élevée avec une IC50 de 07,62 ± 1,56 mg/ml ; en revanche, l’extrait hydroalcoolique de graines de Linum usitatissimum est révélé significativement (p < 0,05) le plus actif avec le test de dénaturation d’albumine d’œuf, dont l’IC50 enregistrée est de 36,86 ± 2,72 mg/ml. D’après les résultats obtenus, on a constaté que les extraits aqueux et hydroalcoolique de graines de Linum usitatissimum possèdent une activité protectrice in vitro contre la dénaturation des protéines qui joue un rôle dans l’entraînement des maladies inflammatoires et arthritiques. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Flavonoïdes |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Extraits de plantes |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Inflammation |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Activité antiarthritique |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Linum usitatissimum L. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Dénaturation des protéines |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Flavonoïdes |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Extraits de plantes |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Inflammation |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Activité antiarthritique |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Linum usitatissimum L. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Dénaturation des protéines |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | L. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Plant extracts |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Flavonoids |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Anti-arthritic activity |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Linum usitatissimum |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Protein denaturation |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Inflammation |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | L. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Plant extracts |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Flavonoids |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Anti-arthritic activity |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Linum usitatissimum |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Protein denaturation |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | Inflammation |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Noui, A. |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohammadi, K. Kouider |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohammadi, R. |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Phytothérapie | 22 | 1 | 2024-01-01 | p. 24-29 | 1624-8597 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://shs.cairn.info/revue-phytotherapie-2024-1-page-24?lang=fr&redirect-ssocas=7080">https://shs.cairn.info/revue-phytotherapie-2024-1-page-24?lang=fr&redirect-ssocas=7080</a> |
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