Le virus BK et physiopathologie des maladies associées (notice n° 978650)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02449cam a2200277 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250125124024.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Solis, Morgane |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Le virus BK et physiopathologie des maladies associées |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2019.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 28 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | BK virus (BKV) is a widely distributed polyomavirus in the world population. It is the causative agent of BKV-associated nephropathy in kidney transplant recipients and hemorrhagic cystitis in bone marrow transplant patients. To date, there is no specific antiviral treatment against BKV. A better understanding of the pathophysiology of BKV-associated diseases, especially in immunocompromised patients, may contribute to the development of novel preventive and therapeutic strategies. After a detailed description of the genomic characteristics of the virus, its replication cycle and available model systems, the pathophysiological and immune mechanisms involved in BKV infection are developed and discussed in this review. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Le virus BK (BKV) est un polyomavirus persistant dans l’organisme, largement répandu dans la population mondiale. Il est responsable d’atteintes majeures chez l’immunodéprimé : la néphropathie à BKV (BKVN) chez les transplantés rénaux et la cystite hémorragique (CH) chez les receveurs de cellules souches hématopoïétiques. À ce jour, il n’existe pas de traitement antiviral spécifique contre le BKV. Une meilleure compréhension de la physiopathologie des infections associées au BKV, notamment chez l’immunodéprimé, permettrait de concevoir des moyens de prévention et de prise en charge adaptés. Après une description détaillée des caractéristiques génomiques du virus, de son cycle de réplication et des modèles d’étude disponibles, les mécanismes physiopathologiques et immunitaires impliqués dans l’infection par le BKV sont développés et discutés dans cette revue. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | réponse immunitaire |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | transplantation |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | polyomavirus |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | immune response |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | transplantation |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | polyomavirus |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gallais, Floriane |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Velay, Aurélie |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Fafi-Kremer, Samira |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Virologie | 23 | 1 | 2019-01-01 | p. 7-22 | 1267-8694 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://shs.cairn.info/revue-virologie-2019-1-page-7?lang=fr&redirect-ssocas=7080">https://shs.cairn.info/revue-virologie-2019-1-page-7?lang=fr&redirect-ssocas=7080</a> |
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