Infections par les virus herpes simplex pendant la grossesse : épidémiologie, aspects cliniques et prise en charge (notice n° 978670)
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| fixed length control field | 03492cam a2200361 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250125124028.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Leruez-Ville, Marianne |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Infections par les virus herpes simplex pendant la grossesse : épidémiologie, aspects cliniques et prise en charge |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2020.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 47 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The incidence of herpes simplex virus (HSV) neonatal infection is estimated to be 8.9 per 100,000 live births in Europe. Early treatment with intravenous acyclovir has transformed the prognosis but this infection remains severe since, despite the treatment, mortality is frequent in disseminated diseases and neurological sequelae are frequent when central nervous system is involved. The major risk factor for transmission is the type of maternal infection. In women shedding the virus in their genital tract during childbirth, neonatal infection rates are 44 %, 25 % and 1.3 % in primary, non-primary and recurrent infections, respectively. The goals for the management of this infection during pregnancy encompass 1) the prevention of any contact between the newborn and the maternal virus by suppressing viral replication in the genital tract in late pregnancy and recommending a cesarean section in cases of genital lesions at delivery, and 2) the development of strategies allowing rapid identification and treatment of infected newborns. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | L’incidence de l’infection néonatale par les virus herpes simplex (HSV) est mal connue ; une modélisation épidémiologique estime cette incidence à 8,9 pour 100 000 naissances vivantes en Europe. Le traitement précoce par l’aciclovir par voie intraveineuse a transformé le pronostic, mais cette infection reste très grave, avec malgré le traitement, un risque de 30 % de mortalité pour les formes disséminées et de 70 % de séquelles neurologiques en cas d’atteinte neuroméningée. Le facteur de risque de transmission majeur est le type d’infection maternelle. En effet, chez les femmes excrétant du virus dans les voies génitales à l’accouchement, le taux d’infection néonatale est de 44 % en cas d’infection initiale primaire, de 25 % en cas d’infection initiale non primaire et de 1,3 % en cas d’infection maternelle récurrente. L’enjeu de la prise en charge de cette infection pendant la grossesse sera 1) de prévenir tout contact du nouveau-né avec le virus par des stratégies de suppression de la multiplication virale dans les voies génitales en fin de grossesse et de préconisation d’une césarienne en cas de lésions génitales à l’accouchement ; et 2) en cas de contact potentiel du nouveau-né avec le virus, de développer une stratégie qui permette une prise en charge rapide de la transmission au nouveau-né. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | valaciclovir |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | HSV-1 |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | virus herpes simplex |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | HSV-2 |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | aciclovir |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | infection néonatale |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | HSV-1 |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | HSV-2 |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | herpes simplex virus |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | neonatal infection |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | acyclovir |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | valacyclovir |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Driessen, Marine |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pichon, Christine |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sellier, Yann |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Charlier, Caroline |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Virologie | 24 | 5 | 2020-09-01 | p. 315-324 | 1267-8694 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://shs.cairn.info/revue-virologie-2020-5-page-315?lang=fr&redirect-ssocas=7080">https://shs.cairn.info/revue-virologie-2020-5-page-315?lang=fr&redirect-ssocas=7080</a> |
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