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Using studies on fiction as an example, the focus is on the conditions, or interdisciplinarity, in human sciences. The intention is to show that theories of fiction rest on diverging principles: thus the word “fiction” neither means nor refers to the same thing for everybody. From this observation, it appears that interdisciplinary practice cannot involve either comparing theories or falsifying them. The relevance of interdisciplinary work thus moves from the theoretical to another level––that of metatheoretical thinking and epistemological consciousness.