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In a global context marked by complex challenges such as climate change and inequality, university-industry collaboration is an essential mechanism for fostering innovative and responsible solutions. This research examines how this partnership can support Responsible Innovation, an emerging paradigm that aligns technological development with societal values and sustainable development. Using a mixed methods approach combining qualitative interviews and quantitative surveys with stakeholders from Moroccan universities and industry the study employs theoretical frameworks from knowledge management and the triple helix model. The findings aim to improve knowledge transfer strategies, enhance business competitiveness, and inform public policy. This research ultimately seeks to enrich the Moroccan innovation ecosystem by promoting socially relevant technologies aligned with the sustainable development goals.