61

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a global pandemic evolving in successive waves. For three years, this health crisis has had a significant impact on organ procurement and transplant activity in France and around the world. In 2020 and 2021, the main impacts of the SARS-CoV-2 epidemic in liver transplantation were the significant decrease in the procurement activity from brain-dead subjects (partially offset by the increase in procurement from Maastricht category III deceased donors), and the decrease in liver transplant activity compared to the pre-COVID reference years. Liver transplant patients, like all immunocompromised patients, paid a heavy price in terms of morbidity and mortality before the development of specific vaccine and treatment strategies.