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Collaboration between doctors and psychologists in the psychological support of patients seems to be a natural process at the moment, and is particularly important in the context of medically assisted reproduction (MAR) that involves gamete donors. The psychological stress caused by MAR can have a negative impact on the outcome. Psychological support can help address issues that are not discussed during the medical consultation. It is all the more important because patients need to be aware of the process they are embarking on and the consequences it will entail. The psychologist will be able to work on the mourning of the dream journey, and enable acceptance of this new mode of conception. Psychological support for patients undergoing MAR with gamete donors brings added value to the medical process, and could improve the effectiveness of treatment.