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This article provides an empirical analysis of the impact of regime changes on the composition and patterns of recruitment of the Portuguese ministerial elite. The violent nature of most regime transformations accounts for the extensive replacements of the political personnel, namely of the uppermost officeholders. In the case of Cabinet members, such discontinuities did not imply, however, radical changes in their social profile, and a series of salient characteristics has persisted over time. The typical Portuguese minister is a male in his mid-forties, of middle-class origin and predominantly urban-born, highly educated and with a state servant background. The two main occupational contingents have been that of the university professors – except for the First Republic (1910-26) – and the military, the latter having only eclipsed with the consolidation of contemporary democracy. As regards career pathways, the most striking feature is the secular trend for the declining role of parliamentary experience, which the democratic regime did not clearly reverse.