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This theory-oriented paper puts forward an integrative conceptual framework to characterize the responsible entrepreneur. It revisits the four paradigms in entrepreneurial research identified by Verstraete and Fayolle (2005) through works stemming from different fields in the literature. The research produces a set of four theoretical propositions and a five-dimension model. The sustainability-driven responsible entrepreneur appears to be: (1) motivated by ethical values and convictions; (2) intent to achieve goals that create renewed societal value; (3) able to develop capacities for reflexive judgment and dynamic capabilities to innovate responsibly and sustainably; (4) expressing relational capacities that can serve stakeholder management.