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This study aims to describe the level of satisfaction among patients and their families according to type of hospital and the socio-demographic characteristics of patients hospitalized in Ho Chi Minh City (HCMC), Vietnam. The study is based on a sample of 538 patients and their families from all hospitals in HCMC, to whom an evaluation questionnaire was given, to be filled out on the day of their release. The average age was 39, and 65.4%  were women. The scores measuring the level of satisfaction varied from 57.7 to 90.7 (on a scale of 0 to 100). The section headed “Treatment Provided by the Doctors” received the highest scores (90.7). Dissatisfaction was primarily associated with factors such as the amount of time spent waiting, the behavior of hospital staff, cleanliness, the cafeteria, and parking for motorbikes. Almost 100% of the patients spoke about their experiences during their stay in the hospital, and 50.2% had some negative opinions (1,042 complaints registered). The older patients, with a lower level of education and living either in other cities or in rural regions around HCMC, tended to be more satisfied than the younger patients, who have higher levels of education and generally reside in suburban or urban areas of HCMC. Those patients who judged their condition to be very serious and their problems serious enough to justify hospitalization and who felt that their health and condition had improved by the time of release compared to the time of admission were more satisfied than the other patients. Hospitalized patients who had an individual room in a specialized hospital tended to be more satisfied than those who shared a room with many patients in a general hospital or in the emergency area of a specialized hospital. No correlation was observed between the level of satisfaction and the patient’s gender. The results of this study highlight the fact that certain domains, notably the hospital’s environment, should be reviewed and examined by healthcare administrators and managers in order to ensure the quality of patient care.