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Psychical dependence during adolescence is here approached from two angles: the Ego/other relation and the inside/outside polarity. In this passage from childhood to adulthood, the experience of separation from the object is the central component of the issue of dependence, particularly when it comes to addictions. We will try to show the paradoxical nature of separation process in adolescence, its primary and Oedipal core whose interweaving provides the basis for its impasses.