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As a central constituent of the future Articella, the Ars medicine is a corpus of medical texts of primary importance for medical teaching in Salerno in the twelfth century. The set text for urology within this corpus was the Liber urinarum Theophili, the Latin translation of a Byzantine text with a practical outlook. For their commentaries on this short treatise, the Salernitan masters also drew on the Liber urinarum Isaac, a fairly comprehensive account on the subject that had been translated from the Arabic by Constantine the African at the end of the eleventh century. This article will assess the doctrinal importance that Isaac’s work assumed in the commentaries written by Bartholomew and Maurus of Salerno.