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Children and adolescents carrying Developmental Coordination Disorder (DCD) form a heterogeneous group associating clumsiness, developmental dyspraxia and tac. Now, and since 1994, international consensus recommends the use of the term DCD in research and clinical practice thus identifying children with minor motor coordination disorders of developmental origins. Recent studies exploring semiotics in children and adolescents with a DCD, with a thorough investigation on the neuro-psychomotor, psychological, neuropsychological and neurovisual levels, are enabling differential diagnoses to be established. The studies show up clinical criteria predicting pure tac sub-groups: (ideomotor [im] and visual-spatial and/or visual-constructive [vsc]), and a group of mixed tac (mx), associating the two preceding groups (im and vsc) but including the specific disorders of motor coordination, with a comorbidity of discrete signs and of cognitive impairment. We will illustrate the approach and clinical procedure and therapeutic indications.