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The objective of this paper is to analyze the conditions for the emergence of collaboration between firms grouped in creative clusters. According to the economy of proximity, the dynamics of a cluster are characterized by the gathering of two forms of proximity: geographical proximity and organized proximity. A quantitative study, a network analysis, and a qualitative study were conducted to analyze the contribution of different forms of proximity (social, cognitive, organizational, and institutional) to the emergence of collaborations between businesses. We highlight three main results: (1) collaborations between creative firms need “gatekeepers”; (2) they also need specific plans, amongst which the way the place is structured is highly important; and (3) the proximity of values appears as a key condition for collaborations.