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Colorectal cancer is a major public health issue and is the fourth most common cancer in the world. 75% of patients suffering from the disease undergo surgical resection, the only curative method currently available. Most recurrences are metastatic (80%) and occur within the first 3 years after surgery. An increasing number of recurrences are being treated with curative intent, necessitating appropriate post-operative monitoring. In France, physical examination, abdominal ultrasound, and chest X-ray are the standard procedures for post-operative monitoring. These examinations should be repeated regularly: every 3 months for 3 years, then every 6 months for 2 years. Based on recent data (national French recommendations, Grade B), CEA testing is no longer recommended, except for monitoring its post-operative normalization. Post-operative endoscopic surveillance is recommended at 1 year, then at 3 years and at 5 years if the surveillance colonoscopy performed is normal. If the initial colon examination is incomplete, a colonoscopy should be completed within 6 months of surgery. Screening for and treating functional digestive sequelae is an essential part of follow-up.